Caspase 1 Inhibitor
Lead Inventor: Craig Thomas (NCATS)
Inventor(s): Matthew Boxer (NCATS)
Ref. No.: E-308-2009/0
Abstract: Novel and potent caspase 1 inhibitors are available for licensing. In particular, this technology discloses potent and selective caspase 1 inhibitors that target the active site of the enzyme.
A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3-Cyanopropanoic Acid Moiety • ChemMedChem • May 3, 2010 • NCATS Chemical Genomics Center