Through A Specialized Platform for Innovative Research Exploration (ASPIRE), NCATS proposes to transform chemistry from an individualized craft to a modern, information-based science. By addressing long-standing challenges in the field of chemistry, including lack of standardization, low reproducibility and an inability to predict how new chemicals will behave, ASPIRE is designed to bring novel, safe and effective treatments to more patients more quickly at lower cost.
The 2020 ASPIRE Reduction-to-Practice Challenge aimed to spur the development of a comprehensive integrated platform for translational innovation in pain, opioid use disorder and overdose.
Through the ASPIRE Design Challenges, NCATS is using the ASPIRE platform to support the Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM. The 2018 NCATS ASPIRE Design Challenges were launched to encourage innovative and catalytic approaches toward solving the opioid crisis.