The aim of the NCATS Chemistry Technology program is to provide cutting-edge resources to enable the broader biomedical research community to pursue basic and translational studies in a faster and more in-depth manner. To achieve this, chemistry technology scientists at NCATS engage in a variety of innovative translational research activities. Read the latest news about these activities below.
NCATS Ignites Translational Science Spark for Young Investigators
Through the NIH Oxford-Cambridge Scholars Program, two graduate students are working with NCATS Chemistry Technology program scientists and researchers at the University of Cambridge to help further their research efforts. Their scientific projects focus on finding ways that the malaria parasite becomes resistant to drugs and identifying new methods to see what genes are turned on in tumor cells.
Researchers Hit the Brakes on Lethal Brain Cancers in Mice
New research conducted in mice provides evidence that highly lethal brain tumors, called high-grade gliomas, stop growing when deprived of a specific molecule naturally produced when brain cells fire.
Ketamine Lifts Depression via a Byproduct of Its Metabolism
A chemical byproduct, or metabolite, created as the body breaks down ketamine likely holds the secret to the drug’s rapid antidepressant action, NIH scientists and grantees have discovered. This metabolite singularly reversed depression-like behaviors in mice without triggering any of the anesthetic, dissociative or addictive side effects associated with ketamine.