Adenine Team
Scientific Areas of Focus
- Cancer
- Deubiquitinating enzymes
- Epigenetics
- DNA damage and replication
- Infectious diseases
Team Members
Biology Team Lead: Anton Simeonov, Ph.D.
Chemistry Team Lead: Juan Marugan, Ph.D.
Research Scientists:
- Bolormaa Baljinnyam, Ph.D., biology
- Ganesha Bantukallu, chemistry
- George Dorjsuren, biology
- Xin Hu, Ph.D., informatics
- Sankalp Jain, Ph.D., informatics
- Dan Jansen, chemistry
- Steve Kales, Ph.D., biology
- Diane Luci, M.S., chemistry
- Natalia Martinez, Ph.D., biology
- Katie Pohida, chemistry (Intramural Research Training Award fellow)
- Hongmao Sun, Ph.D., informatics
- Shyh-Ming Yang, Ph.D., chemistry
- Adam Yasgar, biology
Guanine Team
Scientific Areas of Focus
- Cancer
- Enzymatic assays
- Kinases
- Metabolic targets (cancer and inborn errors of metabolism)
- Cellular thermal shift assays
- High-throughput cell-based models and high-content screening
Team Members
Biology Team Lead: Matt Hall, Ph.D.
Chemistry Team Lead: Juan Marugan, Ph.D.
Informatics Team Lead: Min Shen, Ph.D.
Research Scientists:
- Ken Cheng, Ph.D., biology
- Nathan Coussens, Ph.D., biology
- Surendra Karavadhi, chemistry
- Colin Kelly, biology
- Li Liu, M.S., chemistry
- Dan Urban, biology
- Ya-Qin Zhang, biology
- Wei Zhao, biology
- Hu Zhu, Ph.D., biology
Thymine Team
Scientific Areas of Focus
- Cancer
- Induced pluripotent stem cell–based assays (retinal pigment epithelium, neurological disorders)
- Advanced cell-based models of disease
- 3-D cell culture and tissue/organoid models
- Immunological and differentiation assays
- Autophagy
- Yeast/bacterial assays
Team Members
Biology Team Lead: Mark J. Henderson, Ph.D.
Chemistry Team Lead: Juan Marugan, Ph.D.
Informatics Team Lead: Noel Southall, Ph.D.
Research Scientists:
- Elena Barnaeva, biology
- Raul Calvo, M.S., chemistry
- Chris Dextras, biology
- Andrés Dulcey, Ph.D., chemistry
- Rajarshi Guha, Ph.D., informatics
- Xin Hu, Ph.D., informatics
- Madhu Lal-Nag, Ph.D., biology
- Samarjit Patnaik, Ph.D., chemistry
- Tej Poudel, Ph.D., medicinal chemistry
- Wenjuan Ye, M.B., biology
- Xiaohu Zhang, biology