Saturday, January 23, 2016 – 8:30 a.m. – 5:30 p.m. PST
San Diego Convention Center, San Diego, CA, USA
8:30 – 8:40 a.m.: Robust or Go Bust: An Introduction to the Assay Guidance Manual
Nathan P. Coussens, Ph.D., NCATS, NIH
8:40 – 9:20 a.m.: Establishing Robust Biochemical Assays
Lisa Minor, Ph.D., In Vitro Strategies, LLC
9:30 – 10:10 a.m.: Treating Cells as Reagents to Design Reproducible Screening Assays
Terry Riss, Ph.D., Promega Corporation
10:20 – 11:00 a.m.: Assay Interpretation: Studies in Mechanisms and Methods in Assay Interferences
Douglas Auld, Ph.D., Novartis Institutes for BioMedical Research
11:10 – 11:50 a.m.: Biophysical Approaches to Small Molecule Discovery and Validation
Michelle Arkin, Ph.D., University of California, San Francisco
12:00 – 1:00 p.m.: Lunch
1:00 – 1:40 p.m.: Basic Assay Statistics, Data Analysis and Rules of Thumb
Thomas D.Y. Chung, Ph.D., Mayo Clinic
1:50 – 2:30 p.m.: Reproducibility and Differentiability of Compound Potency Results from Screening Assays in Drug Discovery
V. Devanarayan, Ph.D., AbbVie Inc.
2:40 – 3:20 p.m.: Application of Quantitative High Throughput Screening in Toxicity Testing
Menghang Xia, Ph.D., NCATS, NIH
3:30 – 4:10 p.m.: In Vitro Assessment of ADME Properties of Lead Compounds
4:20 – 5:30 p.m.: Small Group Breakout Sessions
Acknowledgements: Chris Austin, Laura Carter, Nicholas Gelardi, Steven Hamilton, Sandy Ismail, Cindy McConnell, Amy McGorry, Anton Simeonov, and Geoff Spencer