Saturday, February 4, 2017 — 8:40 a.m. - 6:00 p.m. ET
Walter E. Washington Convention Center, Room 152A, Washington, D.C. 20001, USA
8:40 - 9:00 a.m.: Robust or Go Bust: An Introduction to the Assay Guidance Manual
G. Sitta Sittampalam, Ph.D., NCATS, NIH
9:10 - 9:55 a.m.: Treating Cells as Reagents to Design Reproducible Screening Assays
Terry Riss, Ph.D., Promega Corporation
10:00 – 10:15 a.m.: Beverage Break
10:15 - 11:00 a.m: Strategies for Assay Selection and for the Development of Robust Biochemical Assays
Nathan P. Coussens, Ph.D., NCATS, NIH
11:10 - 11:55 a.m.: Assay Interpretation: Studies in Mechanisms and Methods in Assay Interferences
Douglas Auld, Ph.D., Novartis Institutes for BioMedical Research
12:00 - 12:50 p.m.: Lunch
12:50 - 1:35 p.m.: Biophysical Approaches to Small Molecule Discovery and Validation
Michelle Arkin, Ph.D., University of California, San Francisco
1:45 - 2:30 p.m.: Basic Assay Statistics, Data Analysis and Rules of Thumb
Thomas D.Y. Chung, Ph.D., Mayo Clinic
2:30 - 2:45 p.m.: Beverage Break
2:45 - 3:30 p.m.: Reproducibility and Differentiability of Compound Potency Results from Screening Assays in Drug Discovery
V. Devanarayan, Ph.D., AbbVie, Inc.
3:40 - 4:25 p.m.: In Vitro Toxicological Testing in a qHTS Platform
Menghang Xia, Ph.D., NCATS, NIH
4:35 - 5:20 p.m.: In Vitro Assessments of ADME Properties of Lead Compounds
Xin Xu, Ph.D., NCATS, NIH
5:30 - 6:00 p.m.: Open Discussion Session
Acknowledgements: Amy McGorry, Meghan Schofield, Steven Hamilton, James E. McGee, Steven D. Kahl, Jeffrey R. Weidner, Chris Austin, Nicholas Gelardi, Sandy Ismail, Terry LaMotte, Cindy McConnell, Anton Simeonov, and Geoff Spencer