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Assay Guidance Workshop Agenda - February 2017

Saturday, February 4, 2017 — 8:40 a.m. - 6:00 p.m. ET

Walter E. Washington Convention Center, Room 152A, Washington, D.C. 20001, USA

8:40 - 9:00 a.m.: Robust or Go Bust: An Introduction to the Assay Guidance Manual
G. Sitta Sittampalam, Ph.D., NCATS, NIH

9:10 - 9:55 a.m.: Treating Cells as Reagents to Design Reproducible Screening Assays
Terry Riss, Ph.D., Promega Corporation

10:00 – 10:15 a.m.: Beverage Break

10:15 - 11:00 a.m: Strategies for Assay Selection and for the Development of Robust Biochemical Assays
Nathan P. Coussens, Ph.D., NCATS, NIH

11:10 - 11:55 a.m.: Assay Interpretation: Studies in Mechanisms and Methods in Assay Interferences
Douglas Auld, Ph.D., Novartis Institutes for BioMedical Research

12:00 - 12:50 p.m.: Lunch

12:50 - 1:35 p.m.: Biophysical Approaches to Small Molecule Discovery and Validation
Michelle Arkin, Ph.D., University of California, San Francisco

1:45 - 2:30 p.m.: Basic Assay Statistics, Data Analysis and Rules of Thumb
Thomas D.Y. Chung, Ph.D., Mayo Clinic

2:30 - 2:45 p.m.: Beverage Break

2:45 - 3:30 p.m.: Reproducibility and Differentiability of Compound Potency Results from Screening Assays in Drug Discovery
V. Devanarayan, Ph.D., AbbVie, Inc.

3:40 - 4:25 p.m.: In Vitro Toxicological Testing in a qHTS Platform
Menghang Xia, Ph.D., NCATS, NIH

4:35 - 5:20 p.m.: In Vitro Assessments of ADME Properties of Lead Compounds
Xin Xu, Ph.D., NCATS, NIH

5:30 - 6:00 p.m.: Open Discussion Session

Acknowledgements: Amy McGorry, Meghan Schofield, Steven Hamilton, James E. McGee, Steven D. Kahl, Jeffrey R. Weidner, Chris Austin, Nicholas Gelardi, Sandy Ismail, Terry LaMotte, Cindy McConnell, Anton Simeonov, and Geoff Spencer

Last updated: 05-08-2017
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