February 3, 2018 — 8:00 a.m. - 5:00 p.m.
San Diego Convention Center, 111 W Harbor Drive, San Diego, CA 92101
8:00-8:45 a.m.: Strategies for Assay Selection and for the Development of Robust Biochemical Assays
Nathan P. Coussens, Ph.D., NCATS/NIH
8:50-9:35 a.m.: Treating Cells as Reagents to Design Reproducible Screening Assays
Terry Riss, Ph.D., Promega Corporation
9:45-10:00 a.m.: Beverage Break
10:00-10:45 a.m.: Assay Interpretation: Studies in Mechanisms and Methods in Assay Interferences
Douglas Auld, Ph.D., Novartis Institutes for BioMedical Research
10:55-11:15 a.m.: Robust or Go Bust: An Introduction to the Assay Guidance Manual
G. Sitta Sittampalam, Ph.D., NCATS/NIH
11:15-12:00 p.m.: Lunch
12:00-12:45 p.m.: Biophysical Approaches to Small Molecule Discovery and Validation
Michelle Arkin, Ph.D., University of California, San Francisco
12:55-1:40 p.m.: In Vitro Toxicological Testing using a qHTS Platform
Menghang Xia, Ph.D., NCATS/NIH
1:45-2:00 p.m.: Beverage Break
2:00-2:45 p.m.: In Vitro Assessments of ADME Properties of Lead Compounds
Xin Xu, Ph.D., NCATS/NIH
2:55-3:40 p.m.: Basic Assay Statistics, Data Analysis and Rules of Thumb
Thomas D.Y. Chung, Ph.D., Mayo Clinic
3:50-4:35 p.m.: System Suitability of In Vitro Screening Assays in Drug Discovery
V. Devanarayan, Ph.D., Charles River
4:45-5:00 p.m.: Open Discussion