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Assay Guidance Workshop Agenda — October 2017

Monday, October 23, 2017 — 8:00 a.m. - 6:30 p.m. ET

University of North Carolina at Chapel Hill, North Carolina, 27599, USA

8:00 - 8:15 a.m.: Robust or Go Bust: An Introduction to the Assay Guidance Manual
G. Sitta Sittampalam, Ph.D., NCATS, NIH

8:20 - 9:00 a.m.: Statistical Design of Experiments for Assay Development
Steven D. Kahl, Eli Lilly and Company

9:10 - 9:50 a.m.: Treating Cells as Reagents to Design Reproducible Screening Assays
Terry Riss, Ph.D., Promega Corporation

10:00 - 10:15 a.m.: Beverage Break

10:15 - 10:55 a.m.: Assay Development for High Content Screening
O. Joseph Trask, Jr., Ph.D., PerkinElmer

11:05 - 11:45 a.m.: Label-Free HTS Assays using Mass Spectrometry
James McGee, Ph.D., Eli Lilly and Company

11:55 a.m. - 12:45 p.m.: Lunch

12:45 - 1:25 p.m.: Assay Interpretation: Studies in Mechanisms and Methods in Assay Interferences
Douglas Auld, Ph.D., Novartis Institutes for BioMedical Research

1:35 - 2:15 p.m.: Assay Interference by Chemical Reactivity
Jayme L. Dahlin, M.D., Ph.D., Brigham and Women's Hospital

2:15 - 2:30 p.m.: Beverage Break

2:30 - 3:10 p.m.: Basic Assay Statistics, Data Analysis and Rules of Thumb
Thomas D.Y. Chung, Ph.D., Mayo Clinic

3:20 - 4:00 p.m.: Reproducibility and Differentiability of Compound Potency Results from Screening Assays in Drug Discovery
V. Devanarayan, Ph.D., AbbVie, Inc.

4:10 - 4:50 p.m.: Assay Operations: Keeping your Assays Robust and Reproducible
Jeffrey R. Weidner, Ph.D., QualSci Consulting, LLC

4:50 - 5:00 p.m.: Beverage Break

5:00 - 5:40 p.m.: In Vitro Toxicological Testing using a qHTS Platform
Menghang Xia, Ph.D., NCATS, NIH

5:50 - 6:30 p.m.: In Vitro Assessments of ADME Properties of Lead Compounds
Xin Xu, Ph.D., NCATS, NIH

6:30 - 7:30 p.m.: Reception

Last updated: 08-31-2017
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