Functional Genomics Lab projects at NCATS span a wide range of diseases and fundamental biological processes.
Selected Functional Genomics Lab Projects
- RNAi Screen for Genes Involved in the Recruitment of Parkin to Damaged Mitochondria
- RNAi Screen for Genes that Prevent DNA Re-Replication
- RNAi Screen for Modulators of Topoisomerase 1 Poisons in Breast Cancer Cells
Project Areas
Cancer
- Drug enhancer/resistance screens
- DNA-damaging agents
- Immunotoxins
- Molecular targets in cancer
- Breast cancer
- Melanoma
- Cancer-related pathways
- NF-κB
- Migration
Infectious diseases
- Viral infection and replication
- Poxvirus
- HIV
- Ebola virus
- Hepatitis C virus
- Immune response
Fundamental cell biology
- DNA replication
- Reprogramming/differentiation
Other disease-related phenotypes
- Parkinson’s disease
- Diabetes
- Fragile X syndrome