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New Method Could Help Find Potential Treatments for Rare Diseases

Scientists in NCATS’ Assay Development and Screening Technology program are developing new methods for screening small molecules that could help researchers test possible drugs and develop new treatments for many diseases.

I‐Corps at NIH: Entrepreneurial Training Program Creating Successful Small Businesses

This commentary highlights the 36‐month longitudinal study following the pilot cohort of the Innovation‐Corps at the National Institutes of Health program.

Collaborate with NCATS Scientists on the NIH HEAL InitiativeSM

NCATS welcomes HEAL-related proposals to advance promising compounds and human cell-based models through preclinical development in collaboration with NCATS’ intramural scientists.

DIAMOND Portal Offers Research Training for All

Staff who work on clinical studies can improve their skills with high-quality training materials on the DIAMOND portal. The goal of the CTSA Program-supported DIAMOND project is to create well-run clinical trials through well-trained staff.

Working Together at Rare Disease Day at NIH

Rare Disease Day at NIH, held this year on Feb. 28, exemplifies NCATS’ approach to rare diseases research: involving patients as partners throughout the translational research process to ensure that research and interventions address patients’ needs.

Taking Stock and Action in the Opioid Crisis

In February, NCATS co-hosted a two-day symposium for pain and addiction researchers as part of the NIH HEAL (Helping to End Addiction Long-termSM) Initiative.

NCATS Assay on Top 10 Scientific Achievements List

A scientific society honored NCATS scientists for creating a screening test to identify molecules that block the growth of new blood vessels. The test could be useful in cancer research.

Understanding Out-of-Control Inflammation

Scientists at Brigham and Women’s Hospital collaborated with NCATS high-throughput screening experts to develop a different approach against inflammation, identifying four compounds that can potentially turn on anti-inflammatory activity.

Opioids Increase the Risk of Pneumonia

NIH-supported research suggests a new danger associated with opioids: They can increase a person’s risk for pneumonia that is severe enough to warrant hospitalization.

Director's Corner

Christopher P. Austin, M.D.

May Director's Message

For millennia, physicians have diagnosed human ailments by categorizing symptoms and then treating patients according to these preformed categories. While this approach has been enormously valuable in allowing health care providers to effectively identify, understand and manage many diseases, every doctor knows that each patient’s disease is unique in presentation, course and response to treatment.

Christopher P. Austin, M.D.

In the Spotlight

Clinical and Translational Science Awards Program

Table of Funded Activities 2014 - 2018 (PDF - 121KB)

Apply Now for the ASPIRE Design Challenges

ASPIRE Design challenges badgesThe NCATS ASPIRE Design Challenges are designed to advance innovative and catalytic approaches towards solving the opioid crisis by developing “A Specialized Platform for Innovative Research Exploration” (ASPIRE) to aid in the discovery and development of novel and effective treatments, while at the same time making the process faster and more cost-effective.  The NCATS ASPIRE Design Challenges are part of the of the NIH’s Helping to End Addiction Long-term (HEAL) initiative to speed scientific solutions to the national opioid public health crisis. Learn more about the ASPIRE Design Challenges