Staff Profile: Alice Chen

Alice Chen, M.D.

Medical Officer

Office of Rare Diseases Research

National Center for Advancing Translational Sciences

National Institutes of Health

Email Alice Chen


Alice Chen joined NCATS in November 2017 as a medical officer in the Office of Rare Diseases Research (ORDR). She works with the ORDR team to advance diagnosis and treatment for rare diseases through research. Chen came to NCATS from the Food and Drug Administration (FDA), where she had been working since 2014 in the Office of Translational Sciences, which is part of the Center for Drug Evaluation and Research (CDER). Chen worked on demographic subgroup data collections and analyses, among other knowledge management initiatives. She also helped to lead the development of regulatory science informatics and focused on ways to better capture, develop and effectively use CDER’s institutional knowledge to achieve FDA’s public health objectives.

Chen received her bachelor’s degree in biochemistry and molecular biology from the University of Maryland, Baltimore County, and her medical degree from University of Maryland School of Medicine.

Research Topics

Chen’s research interests include the demographic representation of participants in clinical research, the use of biomedical informatics to promote high-quality data capture to inform rare diseases research and programs, and the advancement of regulatory science to facilitate the efficient development of rare disease therapeutics.

Selected Publications

  1. Representation of Women and Minorities in Clinical Trials for New Molecular Entities and Original Therapeutic Biologics Approved by FDA CDER from 2013 to 2015.
  2. Imaging protein-protein interactions by Förster resonance energy transfer (FRET) microscopy in live cells.