Pramod Terse, a lead toxicologist in the Therapeutic Development Branch within NCATS’ Division of Preclinical Innovation, directs and manages the preclinical regulatory and nonregulatory safety evaluation of small and large molecules supported by the Center.
Prior to joining NCATS, Terse worked as a lead toxicologist in the Developmental Therapeutics Program within the Division of Cancer Treatment and Diagnosis at the National Cancer Institute. Terse is a veterinarian with more than 25 years of experience in his specialized filed of toxicology and pharmacology. He has worked as a lead regulatory toxicologist/risk assessor at the U.S. Environmental Protection Agency in the Health Effects Division to help regulate the use and approval of chemicals based on human risk assessment. Terse gained significant experience in closely related fields, such as laboratory animal medicine and pathology, while working at the Duke University Medical Center as a clinical veterinarian, where he oversaw a large number of studies involving animal models of diseases and preclinical research and testing.
Terse received his doctorate in toxicology and pharmacology from Auburn University, Auburn, Alabama, and maintains certifications from the American Board of Toxicology and the American Board of Veterinary Toxicology. He also has contributed to more than 30 pharmaceutical Investigational New Drug applications, more than 10 risk assessment regulatory reports, and more than 20 peer-reviewed journal articles. Terse has received several NIH and NCATS Directors’ awards.
Terse’s research interests are focused on improving the in vitro and in vivo safety evaluation of therapeutics, better understanding the mechanisms of toxicities, using innovative technologies to facilitate drug discovery, and making the drug development process more time- and cost-effective.
He maintains memberships in the Society of Toxicology and the American Veterinary Medical Association. Terse has gained broad understanding and experience in the clinical, regulatory and managerial research areas of the drug discovery and development processes.