NCATS appreciates the extensive input from its staff, the NCATS Advisory Council, the Cures Acceleration Network Review Board, and members of the translational science community in the development of this strategic plan. In particular, NCATS would like to thank the members of the Strategic Plan Working Group for leading the development of this plan: Penny Burgoon, Christine Cutillo, C. Taylor Gilliland, Cindy McConnell and Dorit Zuk.