This is an opportunity for an externship in clinical and translational sciences at Eli Lilly and Company for scholars, trainees and investigators who are supported by the NCATS' Clinical and Translational Science Awards (CTSA) Program. The externship at Eli Lilly, a large pharmaceutical company, will support the training and education of participants in techniques and principles needed for translational research. Education and training will be team oriented, and in areas of mutual interest for the trainee/scholar and Eli Lilly. Scientific, theoretical and practical knowledge will include an appreciation of translational and commercialization challenges in developing and bringing a biotechnology or pharmaceutical product to patients.
The key objective of this NCATS externship program is to enhance translational scientists’ skill sets and competencies in clinical trial design, clinical pharmacology, toxicology, regulatory affairs and other areas critical to the drug development process. It is expected that, at the end of this externship, participants (coming from academia) will understand the work, “language” and culture of another part of the translational ecosystem (industry) and contribute to the growth of a “bilingual” translational workforce that can promote cooperation and collaboration among academic and industry stakeholders.
The externship is an agreement made between Eli Lilly and the participant. The externship is a fully immersive experience and requires commitment of a minimum of six months and up to one year at Eli Lilly’s main headquarters in Indianapolis, Indiana. Each participant will be matched with a mentor and integrated into the scientific project teams at Eli Lilly. Participants will work on intensive, hands-on projects that will expose them to translational science processes and approaches that are relevant to identifying and developing novel diagnostics and therapeutics. It is expected that this intensive experience will help participants understand the mechanisms of a drug’s action, identify strategies in developing compounds, and evaluate PK/PD studies that are used in preclinical and clinical studies as well as the challenges associated with navigating the drug approval process from designing clinical trials to submitting a new Investigational New Drug application to the Food and Drug Administration. Participants will have the opportunity to interact with each other as a cohort in seminars/workshops to foster cross-fertilization of ideas and promote interdisciplinary learning.
This externship opportunity is open to CTSA Program trainees, scholars or investigators supported by CTSA Program hub award* funds who:
- Have a clinical doctoral degree (M.D. or Ph.D.) or its equivalent in biological or biomedical sciences, bioengineering or a related field;
- Have a record of accomplishments in clinical and translational science research;
- Have a keen interest in learning more about drug development and commercialization processes; and
- Are U.S. citizens or permanent residents of the United States.
*Typically, candidates should fit into one of the following three categories:
- CTSA Program KL2 Scholar
- CTSA Program TL1 Trainee
- Early stage investigator conducting research supported under the UL1
Successful applicants will be provided with:
- Four projects from which to choose, two in the area of clinical pharmacology, one in toxicology (pharmacokinetic/pharmacodynamic), and one in regulatory affairs.
- To gain novel training, applicants are encouraged to select projects that are distinct from their academic research projects at their institutions.
- Lodging by Eli Lilly in Indiana.
- Travel costs associated with one roundtrip for participants between their institution and Eli Lilly in Indiana.
Please note that the participants’ stipends or salaries must be provided from the CTSA Program hub awards, as no new additional funds for stipends or salaries are provided with this externship. Letters of commitment from the Principal Investigators (PIs) of the CTSA Program hubs must accompany the applications to ensure that the participants’ stipends/salaries will be provided for the term of the externship (see Application Procedure).
Selected participants are required to:
- Agree to and sign a non-disclosure agreement with Eli Lilly.
- Attend an orientation session at Eli Lilly at the beginning of their experience.
- Showcase their work at the end of the externship at a research symposium at Eli Lilly.
Upon completion of the externship, participants will:
- Be required to complete an exit interview with NCATS staff.
- Be required to complete a post-rotation evaluation.
- Receive a statement of completion.
- Discuss your interests with your CTSA Program hub PI.
- Discuss your interests with the NCATS point of contact prior to applying.
- Apply: Please submit the following application package in PDF format:
- A cover letter signed by the applicant and the CTSA Program hub PI (one page)
- A statement of research interests, your major achievements as a scientist, and a statement as to how this externship will benefit your research program and career development (no more than three pages)
- Indicate your top two project areas, if you were to be selected
- Your NIH biosketch
- Contact information for three references. One of the references must be the PI of the CTSA hub.
All application materials should be submitted by the Authorized Organization Representative via email to email@example.com by May 15, 2017 for consideration.
A review committee comprised of NCATS staff and Eli Lilly mentors and senior staff will review the applications, and a joint meeting will be held to review and select the participants. Announcements will be made by early June with a target start date of July 15, 2017.
Please direct all inquiries to:
Joan Nagel, M.D., M.P.H.
Division of Clinical Innovation
National Center for Advancing Translational Sciences