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The cyclic peptide ipglycermide (iPGM) binds to an iPGM enzyme, blocking the enzyme’s activity

Scientists Advance Parasite and Bacteria Research

NCATS and University of Tokyo scientists have identified the first inhibitor of an enzyme thought to be a potential drug target for fighting disease-causing parasites and bacteria.


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Find out more and contact Nicole Spears to get started.

Assay Development and Screening Technology (ADST)

Advancing therapeutic development through research and development of innovative assay (test) designs and chemical library screening methods. Learn more.

Find NCATS Programs & InitiativesAccess NCATS Expertise & Resources

About ADST

Find out more about the ADST program, its goals, and its progress to date.

Scientific Capabilities

Access state-of-the-art expertise, tools and technologies for assay development and high-throughput screening.

Work with ADST

Learn how to collaborate with the ADST program to develop an assay or screen.

    ADST Projects

    Explore the details behind current ADST program projects.

      ADST in Action

      A collaboration involving a patient advocacy group, pharmaceutical companies, academic researchers and ADST program experts culminated in an innovative advance in drug discovery technology, enabling the team to identify a potential new drug target for one of the most common forms of an inherited neurological disorder called Charcot-Marie-Tooth disease. See more ADST in action.