Skip to main content

NCATS Challenges and Prize Competitions Program

Our program engages a diverse group of people from all over the country to collaborate and stimulate innovative ideas.

NCATS Challenges and Prize Competitions Program

We organize Challenges and Prize Competitions to discover creative solutions to critical issues. See our open Challenges below.

Learn more about Challenges across the federal government.


Open Challenges

Complement-ARIE Challenge

The Complement-Animal Research In Experimentation (Complement-ARIE) program is looking for ideas to boost the creation, standardization, validation, and application of New Approach Methodologies that better imitate human biology. Solutions should include cutting-edge innovations using cell or tissue experiments (in vitro), computer simulations and modeling (in silico), or biochemical assays (in chemico) to replicate human biology, either individually or in combination. It’s important that solutions show a significant step forward from the current advanced technologies.

TARGETED Challenge

The TARGETED (Targeted Genome Editor Delivery) Challenge aims to advance genome editing delivery technology by sourcing innovative solutions for delivering gene editors to somatic cells.


Challenge and Prize Competition Winners

Last updated on December 11, 2023