NCATS research addresses scientific and operational challenges that slow the development of the new interventions to improve human health. The Center aims to make translational science more efficient, less expensive and less risky.
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NCATS Programs & Initiatives
- 3-D Tissue Bioprinting Program
- Stem Cell Translation Laboratory
- Assay Development and Screening Technology (ADST)
- Biomedical Data Translator
- Bridging Interventional Development Gaps (BrIDGs)
- Chemistry Technology
- Discovering New Therapeutic Uses for Existing Molecules
- Genetic and Rare Diseases Information Center (GARD)
- Matrix Combination Screening
- Early Translation Branch (ETB)
- A Specialized Platform for Innovative Research Exploration (ASPIRE)
- A Translational Approach to Addressing COVID-19
- Antiviral Program for Pandemics
- Clinical Trial Readiness for Rare Diseases, Disorders and Syndromes
- Multidisciplinary Machine-Assisted, Genomic Analysis and Clinical Approaches to Shortening the Rare Diseases Diagnostic Odyssey
- National COVID Cohort Collaborative (N3C)
- The Accelerating Medicines Partnership® Bespoke Gene Therapy Consortium (BGTC)
- NIH Common Fund Programs
- Rare Diseases Registry Program (RaDaR)
- Tissue Chip for Drug Screening
- Toxicology in the 21st Century (Tox21)
- Functional Genomics Lab
- Therapeutics for Rare and Neglected Diseases (TRND)
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Research
Mini Organ Models Provide Insights into Genetic Kidney Disease
Researchers combined organ-in-a-dish and organ-on-a-chip technologies to better understand polycystic kidney disease (PKD) and show the role of glucose in forming PKD cysts. This approach could lead to ways to test drugs and develop treatments.
A clinical trial of 1,200 infants undergoing congenital heart disease surgery found that an anti-inflammatory steroid generally did not perform better than placebo at reducing risk of death and other severe outcomes.
Winners of the LitCoin Pilot Design Challenge developed creative plans to construct the LitCoin submission platform. This platform will enable researchers to generate artificial intelligence–ready knowledge and share it with the research community.
Preclinical InnovationImproving the process by which diagnostics and therapeutics are developed.
Clinical InnovationDemonstrating more efficient, collaborative approaches to clinical research.
Strategic Alliances & LicensingSupporting technology development and partnerships to disseminate promising new approaches.
Rare Diseases Research and ResourcesNCATS is committed to using research to address the extraordinary public health issue presented by rare diseases.
Improving the process by which diagnostics and therapeutics are developed.
Demonstrating more efficient, collaborative approaches to clinical research.
Strategic Alliances & Licensing
Supporting technology development and partnerships to disseminate promising new approaches.
Rare Diseases Research and Resources
NCATS is committed to using research to address the extraordinary public health issue presented by rare diseases.
Research at NCATS
NCATS research projects and initiatives focus on addressing scientific and technical challenges to reduce, remove, or bypass bottlenecks in the development of new treatments and tests that will ultimately improve human health. The Center studies translation on a system-wide level to accelerate the development of interventions for more than one disease.
Through its research initiatives, NCATS develops new approaches, technologies, resources, and models; demonstrates their usefulness in a specific disease or case study; and disseminates the data, analyses the methods to the larger scientific community.
NIH-NASA Biomedical Research Activities
NIH and NASA are exploring how biomedical research can address the challenges of deep space exploration and benefit human health in space and on Earth.
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