NCATS research addresses scientific and operational challenges that slow the development of the new interventions to improve human health. The Center aims to make translational science more efficient, less expensive and less risky.
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Research
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Research
Researchers Identify Drugs That Protect Endoplasmic Reticulum Function
NIH researchers identified five U.S. Food and Drug Administration–approved drugs that help maintain healthy calcium levels in the endoplasmic reticulum and prevent proteins from fleeing, which could point to therapies for many diseases.
Systematic Testing Identifies Small-Molecule Cocktail to Improve Stem Cell Survival
NCATS researchers devised a four-part small-molecule cocktail called CEPT to potentially enhance the use of stem cells in research and treating diseases.
NCATS-Funded Researchers Explore Cardiometabolic Benefits of Brown Fat
CTSA Program researchers discover the preventive benefits of brown fat, which could help reduce the risk of heart disease, type 2 diabetes and other cardiometabolic diseases, particularly in people who are obese.
Preclinical InnovationImproving the process by which diagnostics and therapeutics are developed.
Clinical InnovationDemonstrating more efficient, collaborative approaches to clinical research.
Strategic Alliances & LicensingSupporting technology development and partnerships to disseminate promising new approaches.
Patient/Community Engagement & Health InformationEngaging patients in every step of the research process to build trust and improve study quality.
Improving the process by which diagnostics and therapeutics are developed.
Demonstrating more efficient, collaborative approaches to clinical research.
Strategic Alliances & Licensing
Supporting technology development and partnerships to disseminate promising new approaches.
Patient/Community Engagement & Health Information
Engaging patients in every step of the research process to build trust and improve study quality.
Research at NCATS
NCATS research projects and initiatives focus on addressing scientific and technical challenges to reduce, remove, or bypass bottlenecks in the development of new treatments and tests that will ultimately improve human health. The Center studies translation on a system-wide level to accelerate the development of interventions for more than one disease.
Through its research initiatives, NCATS develops new approaches, technologies, resources, and models; demonstrates their usefulness in a specific disease or case study; and disseminates the data, analyses the methods to the larger scientific community.
NIH-NASA Biomedical Research Activities
NIH and NASA are exploring how biomedical research can address the challenges of deep space exploration and benefit human health in space and on Earth.
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