- Pre-Application Webinar for NCATS RFA-TR-20-030, Multi-disciplinary Machine-assisted, Genomic Analysis and Clinical Approaches to Shortening the Rare Diseases Diagnostic Odyssey
- Pre-Application Webinar for NCATS RFA-TR-20-031 and RFA-TR-20-032, Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases
- Assay Guidance Workshop for High-Throughput Screening and Lead Discovery
- 2020 NIH Rural Health Seminar: Challenges in the Era of COVID-19
- Virtual Workshop on Systemic Immunogenicity Considerations for AAV-Mediated Gene Therapy
Sept. 8 – Oct. 23, 2020
Enhance your translational science skills this fall with a seven-week online course, MEDI 501: Principles of Preclinical Translational Science.
Registration for the fall course is open. To register, visit the course website and locate MEDI 501: Principles of Preclinical Translational Science. If you are new to FAES, you will need to follow these steps:
- Click on the “Login” button in the upper right-hand corner of the page
- Click on “Applicant Portal Homepage”
- Click on “Create a New Account” and complete the form
PLEASE NOTE: There is a short wait time after submitting the form while FAES reviews the information submitted. After this review, the account will be activated, and the prospective student will receive an email with the subject heading “Welcome to FAES” and will be able to register for MEDI 501.
An Engaging Case Study Teaching Approach
Translational science is an emerging field that seeks to identify broadly generalizable scientific and operational principles to enhance the effectiveness and efficiency of translational research. In this course, students will learn preclinical translational science principles.
Faculty will teach these principles through a case study of a highly successful translational research partnership involving NCATS, the National Cancer Institute, Northwestern University and the University of Kansas. The partnership produced a promising potential drug shown to inhibit metastasis in animal models, which is being examined in a first-in-human clinical trial in 2020.
Time Requirement and Costs
This one-credit course requires a time commitment of about one hour per week to listen to course lectures and some additional time to complete course readings and other short assignments. It is being offered as a pilot course, with a reduced fee of $50.
- Understand the definitions and goals of translational research and translational science and how they differ.
- Identify a range of scientific and operational principles that can be applied to enhance preclinical translational research projects.
- Learn about the research process necessary to enable a scientific discovery to produce an effective compound that can be used in humans.
- Learn about the varied roles of different disciplines, as well as agencies — including industry, government agencies, and academic faculty and institutions — in advancing translational research and how to facilitate effective interagency and team-based partnerships.
Who Should Participate?
- Individuals at all career stages—from students to senior scientists—and across a variety of roles, including scientists, administrators and experts in scientific collaboration
- Individuals interested in exploring translational science as a research area or career path
- Individuals interested in learning scientific, operational and partnership principles for effective translational research that can be applied to their own work
- Faculty involved in translational science education and training programs
Download the course flyer (PDF - 508KB) for additional details.
Read the course syllabus (PDF - 152KB), including links to faculty bios.
Pre-Application Webinar for NCATS RFA-TR-20-030, Multi-disciplinary Machine-assisted, Genomic Analysis and Clinical Approaches to Shortening the Rare Diseases Diagnostic Odyssey
Oct. 6, 2020
Available now: View the webinar slides. Responses to questions will be posted soon.
NCATS will host a pre-application webinar on Tuesday, Oct. 6, 2020, from 3 p.m. to 4:30 p.m. Eastern Daylight Time for RFA-TR-20-030, Multi-disciplinary Machine-assisted, Genomic Analysis and Clinical Approaches to Shortening the Rare Diseases Diagnostic Odyssey.
NCATS staff will provide an orientation and technical assistance to potential applicants by explaining the goals and objectives of the funding opportunity announcement and answering questions from webinar attendees.
Potential applicants are encouraged to submit their questions to email@example.com by Oct. 2, 2020.
The presentation and responses to questions will be posted here after the webinar.
For more information about the webinar, see NOT-TR-20-037.
Pre-Application Webinar for NCATS RFA-TR-20-031 and RFA-TR-20-032, Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases
Oct. 15, 2020
NCATS will host a pre-application webinar on Thursday, Oct. 15, 2020, from 1 p.m. to 3 p.m. Eastern Daylight Time for RFA-TR-20-031 and RFA-TR-20-032, Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases.
NCATS staff will provide an orientation and technical assistance to potential applicants by explaining the goals and objectives of both FOAs and answering questions from webinar attendees.
Potential applicants are encouraged to submit their questions to firstname.lastname@example.org by Oct. 12, 2020.
The presentation and responses to questions will be posted here after the webinar.
For more information about the webinar, see NOT-TR-20-038.
Nov. 18-19, 2020
Day 1: 8:30 a.m. to 5:30 p.m. EST
Day 2: 8:50 a.m. to 5 p.m. EST
NCATS is hosting a two-day workshop that will cover a broad range of critical concepts underlying assay development and implementation for high-throughput screening and lead discovery projects. This workshop is designed to disseminate critical information about the implementation of robust assay methods and is particularly relevant for researchers developing molecular probes or clinical candidates. Many of the workshop instructors have 20 to 30 years of experience in the field of drug discovery and will share information not readily found in a classroom or published material outside of the Assay Guidance Manual (AGM). It will also cover emerging technologies and modalities in drug discovery, including the use of stem cells, antibody therapeutics, DNA-encoded libraries and advances in COVID-19 therapeutics.
Along with the AGM, this workshop will provide participants with a broad, practical perspective on assay development and data analysis so they can improve research projects involving drug discovery and know where to find further information; identify reagents, methods and instrumentation that are well suited to robust assays; and develop robust assays and the required counter and secondary assays for targets of interest. In addition, the workshop will provide participants with broad overviews and practical perspectives on new and emerging modalities in drug discovery.
Nov. 19, 2020
1 p.m. to 5 p.m. EST
Join NCATS and the National Institute on Minority Health and Health Disparities for the 2020 NIH Rural Health Seminar: Challenges in the Era of COVID-19. The seminar will bring together researchers, medical practitioners and others to explore topics in rural health. Learn and explore the impact of COVID-19 on rural populations, systems and workforce issues, and community engagement to respond to the pandemic.
This seminar will provide an opportunity to engage and explore important issues of rural health. Sessions include:
- Rural Population Impact and Response in the Time of COVID-19
- Researchers and Community Partners Respond to the Challenges of COVID-19
To join the conversation on social media, please use hashtag #RuralHealth.
Nov. 30 – Dec. 1, 2020
The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) and the Center for Biologics Evaluation and Research (CBER) at the U.S. Food and Drug Administration (FDA) are co-hosting a virtual Workshop on Systemic Immunogenicity Considerations for Adeno-Associated Virus (AAV)-Mediated Gene Therapy. This meeting will bring together scientists, therapeutic developers and patient representatives to focus on immunogenicity issues related to the systemic administration of AAV gene therapy products and identify solutions for those issues.
Goals for this meeting are to—
- Exchange lessons learned from AAV gene therapy clinical trials to date, including clinical manifestations of immunogenicity, methods for evaluating the risk of immune responses, effective immunosuppressive protocols and other clinical topics.
- Explore emerging methods and technologies for modulating immune responses to AAV gene therapies with respect to both reducing the immunogenicity of AAV vector molecules and tolerizing strategies.
- Review basic, preclinical and clinical knowledge gaps, including the adequacy of current in-silico algorithms, preclinical models, assays and knowledge-sharing mechanisms to address those gaps.
- Identify and explore potential solutions.
Please submit abstracts by Oct. 1, 2020. Abstracts can be submitted online using this form or by downloading and emailing a fillable PDF to Deanna Portero with the subject line: Abstract Submission for Digital AAV Immunogenicity Workshop.
Jan. 14, 2021
The NCATS Advisory Council will convene a virtual meeting on Jan. 14, 2021. The meeting will feature presentations by NCATS leadership and invited guests. For more information about the Advisory Council, visit the NCATS Advisory Council page of this site.