- Gene-Targeted Therapies: Early Diagnosis and Equitable Delivery
- NCATS Online Course in Translational Science
- LitCoin Stakeholder Feedback Workshop
- Assay Guidance Manual Virtual Workshop on DNA-Encoded Libraries for Lead Discovery
- NCATS Advisory Council Meeting
June 3, June 10 and June 17
12–4:30 p.m. EDT
NCATS, the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke are co-hosting a virtual NIH roundtable meeting — Gene-Targeted Therapies: Early Diagnosis and Equitable Delivery. This meeting will bring together scientists, clinicians, therapeutics developers, patient representatives and economists to discuss challenges and barriers to equitable delivery of gene-targeted therapies to individuals living with rare diseases in a timely manner and identify possible solutions for these issues.
The goals for this meeting are to —
- Explore new and existing approaches to identify all individuals with rare diseases that would benefit from gene-targeted therapies.
- Identify existing systems that can be leveraged or adapted to bring treatments to the individuals who can benefit from them.
- Identify gaps that need to be addressed and solutions to facilitate the effective dissemination of treatments in an equitable manner.
June 14–July 30, 2021
Enhance your translational science skills this summer with a seven-week online course, MEDI 501: Principles of Preclinical Translational Science.
Registration for the summer course is open. To register, go to https://faes.org/courses and locate the course — MEDI 501: Principles of Preclinical Translational Science. If you are new to FAES, you will need to follow these steps:
- Click on the “Login” button in the upper right hand corner of the page
- Click on “Applicant Portal Homepage”
- Click on “Create a New Account” and complete the form
PLEASE NOTE: There is a short wait time after submitting the form while FAES reviews the information submitted. After this review, the account will be activated and the prospective student will receive an email with the subject heading “Welcome to FAES” and will be able to register for MEDI 501.
An Engaging Case Study Teaching Approach
Translational science is an emerging field that seeks to identify broadly generalizable scientific and operational principles to enhance the effectiveness and efficiency of translational research. In this course, students will learn preclinical translational science principles.
Faculty will teach these principles through a case study of a highly successful translational research partnership involving NCATS, the National Cancer Institute, Northwestern University and the University of Kansas. The partnership produced a promising potential drug shown to inhibit metastasis in animal models, which is currently being examined in a first-in-human clinical trial.
This one-credit course requires a time commitment of about one hour per week to listen to course lectures and some additional time to complete course readings and other short assignments.
- Understand the definitions and goals of translational research and translational science and how they differ.
- Identify a range of scientific and operational principles that can be applied to enhance preclinical translational research projects.
- Learn about the research process necessary to enable a scientific discovery to produce an effective compound that can be used in humans.
- Learn about the varied roles of different disciplines, as well as agencies — including industry, government agencies, and academic faculty and institutions — in advancing translational research and how to facilitate effective interagency and team-based partnerships.
Who Should Participate?
- Individuals at all career stages — from students to senior scientists—and across a variety of roles, including scientists, administrators and experts in scientific collaboration
- Individuals interested in exploring translational science as a research area or career path
- Individuals interested in learning scientific, operational and partnership principles for effective translational research that can be applied to their own work
- Faculty involved in translational science education and training programs
Download the course syllabus (PDF - 176KB) to learn more about the course’s key themes and format, which includes both didactic and interactive learning opportunities.
Download the course flyer (PDF - 334KB) for additional details.
June 17–18, 2021
11 a.m.–4 p.m. EDT
NCATS — in collaboration with the National Library of Medicine, The BMJ, Elsevier, The EMBO Press Journals, Faculty of 1000, PLOS and Springer Nature — is hosting a two-day virtual workshop to solicit stakeholder feedback on a potential program to develop a new currency for scientific research, called “LitCoin.” During this workshop, panelists will discuss the difficulties associated with publishing nontraditional research results, examine currently available ways to deposit open data and how it can help or hinder a researcher’s ability to publish later, investigate how credit toward career development may be assigned to researchers for their nontraditional contributions to science; provide perspectives on the ability of current natural language processing technologies, and explore how data currently are reused by other researchers and what roadblocks exist to reusing data, all in the context of the LitCoin concept. Attendees will have the opportunity to contribute comments and questions during the workshop using online collaboration tools.
Day 1: 12:30–5 p.m. EDT
Day 2: 12:15–5:15 p.m. EDT
NCATS’ Assay Guidance Manual (AGM)
program is hosting a two-day virtual workshop to train scientists on the fundamentals and applications of DNA-Encoded Libraries (DEL) technology and engage in a dialogue with those interested in gaining an advanced understanding of the technology. This workshop aims to provide best practices and discuss standards for rigor in the DEL field to enable reproducible results. Through the combined learnings from the four sessions, participants will improve the quality of their research projects by utilizing DEL for hit discovery and know where to find further information. Many of the instructors are pioneers and experienced developers of the technology. The sessions are aimed at sharing DEL fundamentals to facilitate uptake and learning for both novice and established users. Novice users will take home practical learnings that can be immediately applied, and experienced practitioners will gain a deeper appreciation for the complexities of DEL that are outside their immediate disciplines of expertise. This workshop also will provide participants with a sampling of emerging trends and discuss technological hurdles to the advancement of the field.
This workshop will feature seminars that highlight critical concepts about the DEL technology, including DEL design and production, affinity selection strategy and execution, and sequencing and data analysis; it will close with a panel discussion about emerging trends and technological advances in the DEL field.
The NCATS Advisory Council will convene a virtual meeting on Sept. 23–24, 2021. The meeting will feature presentations from NCATS Acting Director Joni L. Rutter, Ph.D., and others about the Center’s initiatives, policies, programs and future direction.
For more information about the Advisory Council, visit the NCATS Advisory Council page of this site.