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Click on the links below or scroll down to view open opportunities in each section.
Please note: Visit the NIH Guide for Grants and Contracts for the most current funding opportunities available from NCATS.
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
RFA-TR-23-016 · Posted Date: 07/05/2023 · Rare Diseases
HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
RFA-NS-23-006 · Posted Date: 09/15/2022 · HEAL
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
RFA-NS-23-007 · Posted Date: 09/15/2022 · HEAL
Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
RFA-TR-22-030 · Posted Date: 06/28/2022 · Rare Diseases
NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)
RFA-HL-23-008 · Posted Date: 11/16/2021 · SBIR/STIR
PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
PA-23-232 · Posted Date: 07/12/2023 · SBIR/STIR
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)
PAR-23-219 · Posted Date: 07/12/2023 · SBIR/STIR
PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
PA-23-230 · Posted Date: 07/12/2023 · SBIR/STIR
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
PA-23-189 · Posted Date: 06/29/2023 · NIH
ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)
PAR-23-199 · Posted Date: 06/06/2023 · Rare Diseases
Accelerating Behavioral and Social Science through Ontology Development and Use: Research Network Projects (U01 Clinical Trial Not Allowed)
PAR-23-182 · Posted Date: 05/24/2023 · NCATS
Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) (R21 Clinical Trials Not Allowed)
PAR-23-177 · Posted Date: 05/11/2023 · NCATS
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)
PAR-23-267 · Posted Date: 04/18/2023 · SBIR/STIR
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (UT1/UT2) Clinical Trial Not Allowed
PAR-23-268 · Posted Date: 04/18/2023 · SBIR/STIR
Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed)
PAR-23-160 · Posted Date: 04/13/2023 · Rare Diseases
Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
PAR-23-159 · Posted Date: 04/13/2023 · Rare Diseases
Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)
PAR-23-171 · Posted Date: 04/06/2023 · Rare Diseases
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
PAR-23-138 · Posted Date: 03/22/2023 · NCATS
NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed)
PAR-23-109 · Posted Date: 03/10/2023 · NCATS
NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed)
PAR-23-109 · Posted Date: 03/10/2023 · NIH
HEAL Commercialization Readiness Pilot (CRP) Program: Embedded Entrepreneurs for Small Businesses in Pain Management (SB1 Clinical Trial Not Allowed)
PAR-23-069 · Posted Date: 01/03/2023 · HEAL
NICHD Research Education Programs (R25 Clinical Trial Not Allowed)
PAR-22-224 · Posted Date: 08/24/2022 · NCATS
Clinical Trial Readiness for Rare Neurological and Neuromuscular Diseases (U01 Clinical Trial Not Allowed)
PAR-22-184 · Posted Date: 05/13/2022 · Rare Diseases
Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed)
PAR-22-073 · Posted Date: 11/19/2021 · SBIR/STIR
Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)
PAR-21-336 · Posted Date: 09/20/2021 · CTSA Program
Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)
PAR-21-339 · Posted Date: 09/20/2021 · CTSA Program
Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science for UM1 CTSA Hub Awards (RC2 Clinical Trials Not Allowed)
PAR-21-340 · Posted Date: 09/17/2021 · CTSA Program
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed
PA-21-345 · Posted Date: 09/10/2021 · SBIR/STIR
Clinical and Translational Science Award (UM1 Clinical Trial Optional)
PAR-21-293 · Posted Date: 07/30/2021 · CTSA Program
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
PA-21-268 · Posted Date: 06/30/2021 · NCATS
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
PA-21-151 · Posted Date: 02/10/2021 · NCATS
Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
PAR-21-121 · Posted Date: 01/04/2021 · CTSA Program
Notice of Special Interest (NOSI): Small Business Initiatives for Innovative tools and Technologies for Improving Outcomes for Maternal Health
NOT-EB-23-005 · Posted Date: 07/26/2023 · SBIR/STIR
Notice of Change to PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional) in Award Information
NOT-TR-23-022 · Posted Date: 06/23/2023 · CTSA Program
Notice of Intent to Publish a Notice of Funding Opportunity (NOFO) for the Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN)
NOT-TR-23-015 · Posted Date: 05/03/2023 · RDCRN
Notice of Termination of PAR-22-100 "Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed)
NOT-TR-23-008 · Posted Date: 04/13/2023 · Rare Diseases
Notice of Termination of PAR-22-101 "Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
NOT-TR-23-009 · Posted Date: 04/13/2023 · Rare Diseases
Notice of Information: NCATS Prior Approval Process for New CTSA Program UM1 and K12 Scholar Projects that Involve Human Subjects Research
NOT-TR-23-007 · Posted Date: 03/07/2023 · CTSA Program
Notice of Clarification to RFA-TR-22-030 “Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)”
NOT-TR-23-004 · Posted Date: 01/10/2023 · Rare Diseases
Notice of NINDS Participation in RFA-TR-22-030: "Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)"
NOT-NS-23-052 · Posted Date: 12/08/2022 · Rare Diseases
Notice of Termination for NOT-TR-22-023 NCATS Notice of Special Interest (NOSI): Research through NCATS Clinical and Translational Science Award (CTSA) Program: High Impact Specialized Innovation Programs (RC2)
NOT-TR-23-002 · Posted Date: 10/25/2022 · CTSA Program
Notice of Special Interest (NOSI): Research through NCATS Clinical and Translational Science Award (CTSA) Program: High Impact Specialized Innovation Programs (RC2)
NOT-TR-23-003 · Posted Date: 10/25/2022 · CTSA Program
Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program KL2/K12 Institutional Career Development Awards as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project
NOT-OD-22-192 · Posted Date: 10/03/2022 · CTSA Program
Notice of Change in Eligibility for CTSA Program Funding Opportunities: PAR-21-336 (K12), PAR-21-339 (R25), PAR-21-338 (T32), and PAR-21-337 (T32)
NOT-TR-22-035 · Posted Date: 10/03/2022 · CTSA Program
Notice of Change to PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional) in Award Information
NOT-TR-22-033 · Posted Date: 07/20/2022 · CTSA Program
Notice of Change to PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional) in Eligibility
NOT-TR-22-032 · Posted Date: 06/22/2022 · CTSA Program
Notice of Special Interest (NOSI): Availability of Administrative Supplements for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project
NOT-OD-22-137 · Posted Date: 06/07/2022 · CTSA Program
Notice of Change in Eligibility to PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional)
NOT-TR-22-024 · Posted Date: 03/23/2022 · CTSA Program
Notice of Change in Award Information to PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional)
NOT-TR-22-025 · Posted Date: 03/21/2022 · CTSA Program
Notice of Change in Funding Opportunity Description and Application and Submission Information to PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional)
NOT-TR-22-026 · Posted Date: 03/21/2022 · CTSA Program
Notice of NIH Participation in the National Robotics Initiative (NRI)
NOT-EB-22-003 · Posted Date: 02/11/2022 · NCATS
Notice of Change to Participant Eligibility, Participant Costs and Other Attachments to Funding Opportunity Announcement PAR-21-339, Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Program (R25)
NOT-TR-22-010 · Posted Date: 11/30/2021 · CTSA Program
Notice of Change to Receipt Date for CTSA Program Funding Opportunities: PAR-21-293 (UM1), PAR-21-336 (K12), PAR-21-340 (RC2), PAR-21-339 (R25), PAR-21-338 (T32), and PAR-21-337 (T32)
NOT-TR-22-007 · Posted Date: 11/12/2021 · CTSA Program
Notice of Change to Expansion of Eligibility of Optional Companion Applications for CTSA Program Funding Opportunities: PAR-21-293 (UM1), PAR-21-340 (RC2), PAR-21-339 (R25), PAR-21-338 (T32), and PAR-21-337 (T32)
NOT-TR-22-008 · Posted Date: 11/12/2021 · CTSA Program
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry and Re-integration into Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed)
NOT-OD-21-134 · Posted Date: 07/23/2021 · NCATS
Notice of Special Interest (NOSI): Administrative Supplement for Providing Technical and Business Assistance (TABA) Funding to SBIR/STTR Awardees (Admin Supp)
NOT-OD-21-062 · Posted Date: 03/22/2021 · SBIR/STIR
Announcement of Childcare Costs for Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellows
NOT-OD-21-069 · Posted Date: 03/01/2021 · NIH
Notice of Special Interest (NOSI): Availability of Administrative Supplements for Childcare Costs for Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellows
NOT-OD-21-070 · Posted Date: 03/01/2021 · NCATS
Final NIH Policy for Data Management and Sharing
NOT-OD-21-013 · Posted Date: 10/29/2020 · NIH
Supplemental Information to the NIH Policy for Data Management and Sharing: Elements of an NIH Data Management and Sharing Plan
NOT-OD-21-014 · Posted Date: 10/29/2020 · NIH
Supplemental Information to the NIH Policy for Data Management and Sharing: Allowable Costs for Data Management and Sharing
NOT-OD-21-015 · Posted Date: 10/29/2020 · NIH
Supplemental Information to the NIH Policy for Data Management and Sharing: Selecting a Repository for Data Resulting from NIH-Supported Research
NOT-OD-21-016 · Posted Date: 10/29/2020 · NIH
Notice of Special Interest: NCCIH Administrative Supplements to NCATS CTSA Programs for Scholars Pursuing Complementary Health Research Career Development
NOT-AT-20-010 · Posted Date: 04/13/2020 · CTSA Program
Reinstatement of NIH SBIR Direct-to-Phase II Authority and Associated Updates to NCATS Platform Delivery Technologies for Nucleic Acid Therapeutics (R43/R44) Funding Opportunity Announcement
NOT-TR-19-004 · Posted Date: 10/15/2018 · SBIR/STIR
Reinstatement of NIH SBIR Direct-to-Phase II Authority and Associated Updates to NIH SBIR Omnibus Solicitations
NOT-OD-19-019 · Posted Date: 10/15/2018 · SBIR/STIR
Targeted Genome Editor Delivery Challenge
· Posted Date: 05/15/2023 · Somatic Cell Genome Editing
To find NCATS Requests for Proposals, visit FedBizOpps, type n01tr into the keyword field and click the search button.
Learn more about the NIH clinical trial requirements for grants and contracts and download slides that highlight policy changes.
This Notice informs the research community of the NCATS policy regarding support of clinical trial activities. The policy is designed to ensure compliance with the 21st Century Cures Act (Cures Act) as well as all pertinent statutes and existing NIH and NCATS policies; and considers the urgency of developing new treatments for rare diseases.
NCATS welcomes your NIH HEAL Initiative-related proposals to advance promising compounds and human cell-based models through preclinical development in collaboration with NCATS' intramural scientists.
As part of NIH HEAL Initiative, NCATS is applying breakthrough approaches of translational science to advance new treatments for opioid misuse and addiction and for pain. Learn more about NCATS' Role in the NIH HEAL Initiative.
Learn more about current funding opportunities for the Clinical and Translational Science Awards (CTSA) Program on the CTSA Program Funding Information page, including recent announcements and frequently asked questions.
