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In the Spotlight

C-Path Launches CURE Drug Repurposing Collaboratory to Accelerate Identification of New Uses of Existing Drugs to Treat Infectious Diseases, Including COVID-19

Critical Path Institute ∙ 06/23/2020 ∙ NCATS

As millions of patients struggle with diseases that lack adequate treatments, there is a critical need to understand how existing drugs can be used in new ways to improve clinical outcomes. Health care professionals use drugs in novel ways as a potential life-saving intervention when no specific approved therapies are available. However, without the ability to share these experiences in a systematic manner, the clinical and research communities cannot benefit from lessons learned.

To address the challenge, the Critical Path Institute announced the launch of the CURE Drug Repurposing Collaboratory funded by the U.S. Food and Drug Administration, in collaboration with NCATS.

June 2020

Blood Test at COVID-19 Diagnosis Can Predict Disease Severity, Study Finds
University of Virginia ∙ 06/29/2020 ∙ CTSA Program
Unexpected Spectrum of Mental Illnesses Found in Patients with Rare Genetic Disorder
UC Davis Health ∙ 06/24/2020 ∙ CTSA Program
C-Path Launches CURE Drug Repurposing Collaboratory to Accelerate Identification of New Uses of Existing Drugs to Treat Infectious Diseases, Including COVID-19
Critical Path Institute ∙ 06/23/2020 ∙ NCATS
OSU Helping to Drive National Institutes of Health Effort to Harness Analytics in COVID-19 Fight
Oregon State University ∙ 06/22/2020 ∙ CTSA Program
Better Measure of 'Good Cholesterol' Can Gauge Heart Attack and Stroke Risk in Some Populations
The University of Texas Southwestern Medical Center ∙ 06/22/2020 ∙ CTSA Program
The Rate We Acquire Genetic Mutations Could Help Predict Lifespan, Fertility
University of Utah Health ∙ 06/19/2020 ∙ NCATS
Identifying New Drug Targets by Illuminating the Druggable Genome
Massachusetts Biotechnology Council ∙ 06/18/2020 ∙ IDG
Alpacas Could Be the Secret Weapon Against COVID-19
University of Kentucky, Center for Clinical and Translational Science ∙ 06/18/2020 ∙ CTSA Program
iTHRIV Announces Incoming 2020 Scholars Program Cohort
University of Virginia ∙ 06/17/2020 ∙ CTSA Program
TransCelerate Broadens Access to Shared COVID-19 Trial Data
BioCentury, Inc. ∙ 06/17/2020 ∙ CTSA Program
Gut Bacteria May Contribute to Abnormal Blood Vessel Formation
NIH Research Matters ∙ 06/16/2020 ∙ NCATS
Intabio Launches Blaze™ System to Accelerate Biotherapeutic Development
Intabio, Inc. ∙ 06/16/2020 ∙ NCATS
Oral Antibiotics Work, Shorten Hospital Stays for IV Drug Users with Infections
Washington University in St. Louis ∙ 06/16/2020 ∙ CTSA Program
Stress-Management Strategies Can Boost Health Care Teams During Pandemic
Rice University ∙ 06/15/2020 ∙ CTSA Program
NCATS Seeks to Create Hub for COVID-19 Data; Regeneron Reports Preclinical Data Backing Antiviral mAb Cocktail
BioCentury, Inc. ∙ 06/15/2020 ∙ CTSA Program
Disrupted Circadian Rhythms Linked to Later Parkinson's Diagnosis
University of California, San Francisco ∙ 06/15/2020 ∙ CTSA Program
Disrupted Circadian Rhythms Linked to Later Parkinson's Diagnosis: Researchers Probe Brain’s 24-Hour Biological Clock for Neurodegenerative Risks
University of California, San Francisco ∙ 06/15/2020 ∙ CTSA Program
Patients with COVID-19 Donate Specimens to Advance Research Efforts
Washington University in St. Louis ∙ 06/11/2020 ∙ CTSA Program
FDA’s CURE ID App Gets a COVID-19 Refresh
Regulatory Affairs Professionals Society ∙ 06/10/2020 ∙ NCATS
Clinical Trial Looks at Antiseptic Nasal Spray and Gargle to Prevent COVID-19 Infections
University of Kentucky, Center for Clinical and Translational Science ∙ 06/10/2020 ∙ CTSA Program
NIH-Funded UNC Study Maps COVID-19 Infection in Nasal Cavity, Airway, Lungs
Federal Laboratory Consortium for Technology Transfer ∙ 06/09/2020 ∙ NCATS
Pilot Program for COVID-19 Research Launches Multiple Projects in Record Time
University of Kentucky, Center for Clinical and Translational Science ∙ 06/09/2020 ∙ CTSA Program
Researchers Design Clinical Trial on Use of Exercise for Severe Liver Disease
ScienceBlog.com ∙ 06/08/2020 ∙ CTSA Program
COVID-19 Rate Low among Pregnant Women, Study Finds
University of Washington ∙ 06/08/2020 ∙ CTSA Program
CURE ID App Lets Clinicians Report Novel Uses of Existing Drugs
Food and Drug Administration ∙ 06/08/2020 ∙ NCATS
Researchers Design Clinical Trial on Use of Exercise for Severe Liver Disease
Penn State ∙ 06/05/2020 ∙ CTSA Program
Translational Research Hub at BU Gets $38.3 Million Renewal from NIH
Boston University School of Public Health ∙ 06/03/2020 ∙ CTSA Program
NCATS Director Discusses Center's Data-focused Approach to COVID-19
Federal Laboratory Consortium for Technology Transfer ∙ 06/03/2020 ∙ RDCRN
Hesperos Demonstrates Innovative Human-on-a-Chip® Approach to Modeling Innate Immune System Response Following Tissue Damage and Acute Inflammation
Hesperos, Inc. ∙ 06/02/2020 ∙ SBIR/STIR, Tissue Chip
Hesperos Demonstrates Innovative Human-On-A-Chip® Approach to Modeling Innate Immune System Response Following Tissue Damage and Acute Inflammation
Hesperos Inc. ∙ 06/02/2020 ∙ Tissue Chip
Pharmaceutical Testing Technology Developed at UCF for Immune Response Shows Promise for Multi-Organ Diseases
University of Central Florida ∙ 06/02/2020 ∙ SBIR/STIR
Expression of Certain Genes May Affect Vulnerability to Post-Traumatic Stress Disorder
McLean Hospital ∙ 06/02/2020 ∙ CTSA Program
Lab-Grown Miniature Human Livers Transplanted into Rats
University of Pittsburgh Medical Center ∙ 06/02/2020 ∙ Tissue Chip
Abstract 19: Targeting Delta133p53 Isoform with Small-Molecule Compounds to Modulate Cellular Senescence
American Association for Cancer Research ∙ 06/01/2020 ∙ NCGC
Does Estrogen Influence Alcohol Use Disorder?
University of Illinois at Chicago ∙ 06/01/2020 ∙ CTSA Program

May 2020

FDA Seeks Input on Rare Disease Clinical Trials Network
Regulatory Affairs Professionals Society ∙ 05/29/2020 ∙ RDCRN
Cancer Therapeutics Start-up Has Roots in NCATS Research Collaboration
Federal Laboratory Consortium for Technology Transfer ∙ 05/29/2020 ∙ NCATS
Nilotinib Appears Safe and Affects Biomarkers in Alzheimer’s Disease Clinical Trial
Georgetown University Medical Center ∙ 05/29/2020 ∙ CTSA Program
Johns Hopkins, Stony Brook & 13 More Institutions Join NIH Collaborative to Build EHR Database for COVID-19 Research
Becker's Hospital Review ∙ 05/28/2020 ∙ CTSA Program
Top Chicago Universities Launch Social Movement to Team Up the Public & Researchers in Fight Against COVID-19 & Other Diseases
The University of Chicago Medical Center ∙ 05/28/2020 ∙ CTSA Program
Mayo Researchers, Minority Communities Team Up to Combat COVID-19 Health Disparities
Mayo Clinic ∙ 05/28/2020 ∙ CTSA Program
UChicago Partners on Effort to Pair Public with Researchers in Fight against COVID-19
University of Chicago ∙ 05/28/2020 ∙ CTSA Program
Emory Researchers Report Lower ICU and Ventilator Mortality in Critically Ill Adults with COVID-19
Emory University, Woodruff Health Sciences Center ∙ 05/27/2020 ∙ CTSA Program
International gnomAD Consortium Releases Its First Major Studies of Human Genetic Variation
Broad Institute ∙ 05/27/2020 ∙ NCATS
A Simple and Readily Available Saline Solution Can Reliably Transport COVID-19 Samples to Testing Labs
Elsevier ∙ 05/27/2020 ∙ CTSA Program
Gathering Big Data to Accelerate COVID-19 Fight
University of North Carolina at Chapel Hill School of Medicine ∙ 05/26/2020 ∙ CTSA Program
Bringing Brigatinib to Neurofibromatosis Type-2 Patients: From Promising Potential to Platform Clinical Trial
Children’s Tumor Foundation ∙ 05/26/2020 ∙ NCATS
Gathering Big Data to Accelerate the COVID-19 Fight
Oregon Health & Science University ∙ 05/26/2020 ∙ CTSA Program
New Testing System Predicts Septic Shock Outcomes
The University of Chicago, Pritzker School of Molecular Engineering ∙ 05/26/2020 ∙ CTSA Program
UK Neurologist Believes MS Diagnosis Guidelines Need Updated
University of Kentucky, Center for Clinical and Translational Science ∙ 05/23/2020 ∙ CTSA Program
Translational Research Hub at BU Gets $38.3 Million Renewal from NIH
Boston University ∙ 05/21/2020 ∙ CTSA Program
Ototoxicity of FDA-Approved Drugs Being Re-Purposed for COVID-19 Treatment
American Academy of Audiology ∙ 05/20/2020 ∙ NCATS
Apps Help COVID Anxiety, Depression
Northwestern University ∙ 05/20/2020 ∙ CTSA Program
The Lancet: First Prospective Study of Critically Ill COVID-19 Patients from New York City Sheds Light on How Virus Affects Adult Patients in USA
EurekAlert! ∙ 05/19/2020 ∙ CTSA Program
Testing for Blood Clotting Abnormalities Reveals which Critically Ill COVID-19 Patients Are at Risk for Thrombotic Events and Need Hemodialysis
American College of Surgeons ∙ 05/15/2020 ∙ CTSA Program
Good News for Menopausal Women Taking Hop Supplements: Tests Show No Drug Interactions
Oregon State University ∙ 05/15/2020 ∙ CTSA Program
Determining Aspirin’s Benefit for Cardiovascular Disease Prevention
Northwestern University Feinberg School of Medicine ∙ 05/15/2020 ∙ CTSA Program
Community Grant Recipient Uses Personal Health Journey to Help Others Prevent Diabetes
University of Kentucky, Center for Clinical and Translational Science ∙ 05/14/2020 ∙ CTSA Program
Acer Therapeutics to Develop Emetine as Potential COVID-19 Treatment in Collaboration with National Center for Advancing Translational Sciences, One of the National Institutes of Health
Acer Therapeutics Inc. ∙ 05/11/2020 ∙ NCATS
Survey to Explore COVID-19 Impact on Rare Diseases Community
Global Genes ∙ 05/11/2020 ∙ RDCRN
Acer Therapeutics to Develop Emetine as Potential COVID-19 Treatment in Collaboration with National Center for Advancing Translational Sciences, One of the National Institutes of Health
Drugs.com ∙ 05/11/2020 ∙ NCATS
Rare Diseases Clinical Research Network Opens Online Survey on COVID-19
Muscular Dystrophy News ∙ 05/11/2020 ∙ RDCRN
UK Researchers Will Lead Study of COVID-19 Immunity
University of Kentucky ∙ 05/11/2020 ∙ CTSA Program
Children’s Tumor Foundation Announces New NF2 Clinical Trial: INTUITT for NF2
Children's Tumor Foundation ∙ 05/08/2020 ∙ NCATS
COVID-19 Trial Finder Provides Simplified Search Process for COVID-Related Clinical Trials
Columbia University, Department of Biomedical Informatics ∙ 05/07/2020 ∙ CTSA Program
Artificial Intelligence Jump Starts Clinical Trial for Rare Genetic Disease
The University of Alabama at Birmingham ∙ 05/07/2020 ∙ Rare Diseases
Racing Against Time: UNM Scientists Studying Ways to Repurpose Older Drugs to Treat COVID-19 Infection
The University of New Mexico ∙ 05/07/2020 ∙ CTSA Program
Teen Obesity, Diabetes or High Blood Pressure May Lead to Prematurely Aged Arteries
American Heart Association, Inc. ∙ 05/06/2020 ∙ NCATS
Tufts CTSI Announces Covid-19 Pilot Studies Grant Recipients
Tufts Clinical and Translational Science Institute ∙ 05/05/2020 ∙ CTSA Program
$55M NIH Grant Advances Clinical and Translational Research at UC San Diego
University of California, San Diego ∙ 05/04/2020 ∙ CTSA Program
Rare Disease Day and the DADA2 Story: It Takes Detective Work to Diagnose Rare Diseases
The NIH Catalyst ∙ 05/01/2020 ∙ Rare Diseases
Ison, Misharin Receive COVID-19 Rapid Response Grants
Northwestern University Clinical and Translational Sciences Institute and Feinberg School of Medicine ∙ 05/01/2020 ∙ CTSA Program

April 2020

At NIH, Christopher Austin ’82 ‘Translates’ Science into Treatment for COVID-19
Princeton Alumni Weekly ∙ 04/29/2020 ∙ NCATS
Kurome Therapeutics to Develop Therapies Targeting Cancer's Ability to Evade Treatment
Kurome Therapeutics ∙ 04/29/2020 ∙ Chemistry Technology, NCATS
Noninvasive Test May Help Some Patients with Melanoma Avoid Lymph Node Biopsy
Mayo Clinic ∙ 04/27/2020 ∙ CTSA Program
Stanford Chemists’ Work on Rare Molecule Aims to Enhance Cell Therapy and Deliver Functional Cure for HIV/AIDS
Stanford University ∙ 04/27/2020 ∙ NCATS
Diffusion Pharmaceuticals Announces Pre-IND Submission to the FDA of Design for TSC Trials to Treat Acute Respiratory Distress Syndrome in COVID-19
Diffusion Pharmaceuticals Inc. ∙ 04/27/2020 ∙ CTSA Program
Clinical Research in the Time of the COVID-19 Pandemic
Medical University of South Carolina ∙ 04/24/2020 ∙ CTSA Program
Could Suicide Risk Be Predicted from a Patient's Records?
Medical Xpress ∙ 04/24/2020 ∙ CTSA Program
Behavioral Intervention, Not Lovastatin, Improves Language Skills in Youth with Fragile X
UC Davis Health ∙ 04/22/2020 ∙ CTSA Program
Diabetes Reversed in Mice with Genetically Edited Stem Cells Derived from Patients
Washington University School of Medicine in St. Louis ∙ 04/22/2020 ∙ CTSA Program
NCATS Funds Facilitate Development of Finger-Stick COVID-19 Test
Federal Laboratory Consortium for Technology Transfer ∙ 04/22/2020 ∙ CTSA Program
NCATS Funding Use of Tissue Chips to Support COVID-19 Research
ALTEX - Alternatives to Animal Experimentation ∙ 04/22/2020 ∙ Tissue Chip
Rutgers University Launches the Nation’s Largest Study of Health Care Workers Exposed to COVID-19
Rutgers, The State University of New Jersey ∙ 04/21/2020 ∙ CTSA Program
Study Explores How Memory Influences Visual Exploration
Northwestern University Feinberg School of Medicine ∙ 04/21/2020 ∙ CTSA Program
Rare Disease Research Progressing, But Could Go Even Faster
NIH Record ∙ 04/17/2020 ∙ Rare Diseases
Penn State Health Hospitals Now Using Plasma from Recovered Patients as Possible Treatment for COVID-19
Penn State College of Medicine ∙ 04/17/2020 ∙ CTSA Program
Researchers Get Important Glimpse Into Microbiome Development in Early Life
The Children’s Hospital of Philadelphia ∙ 04/16/2020 ∙ CTSA Program
Kebotix Raises $11.4 Million in Series A Funding for Rapid Discovery of Chemicals, Materials to Address Global Challenges
Kebotix, Inc. ∙ 04/16/2020 ∙ NCATS
New COVID-19 Biobank at UK Will Support Research
University of Kentucky, Center for Clinical and Translational Science ∙ 04/16/2020 ∙ CTSA Program
CWRU MD-PhD Student and CTSC TL1 Scholar Uriel Kim Wins Prestigious Clinical and Translational Science Award
Case Western Reserve University School of Medicine ∙ 04/15/2020 ∙ CTSA Program
$765,789 Grant to Focus on Racial, Ethnic Health Disparities
University of Arkansas for Medical Sciences ∙ 04/14/2020 ∙ CTSA Program
A Live View of Brain Tumor Growth: Mouse Study Shows How Advancing Glioma Cells Scramble Brain Function, Blood Flow
The Zuckerman Institute, Columbia University ∙ 04/14/2020 ∙ CTSA Program
Clinical Trial Launches to Evaluate Antimalarial Drugs for COVID-19 Treatment
Washington University School of Medicine ∙ 04/09/2020 ∙ CTSA Program
Three New KL2 Scholars Selected for 2020
University of Wisconsin-Madison, Institute for Clinical and Translational Research ∙ 04/09/2020 ∙ CTSA Program
Stanford Researchers Devise Treatment that Relieved Depression in 90% of Participants in Small Study
Stanford Medicine ∙ 04/06/2020 ∙ CTSA Program
The Heartbeats from Space: Heart Tissues Returned to UW Researchers after a Month at the International Space Station
University of Washington, Seattle ∙ 04/06/2020 ∙ Tissue Chip
New Treatment for Childhood Anxiety Works by Changing Parent Behavior
Elsevier ∙ 04/02/2020 ∙ CTSA Program

March 2020

Getting Closer to a Blood Test for Alzheimer’s Disease?
NIH Director’s Blog ∙ 03/31/2020 ∙ RDCRN
SCTR Institute Awarded $24 Million to Advance Translational Research in South Carolina
Medical University of South Carolina ∙ 03/30/2020 ∙ CTSA Program
Developing Better Kidney Disease Models in Microgravity
ISS U.S. National Laboratory ∙ 03/30/2020 ∙ Tissue Chip
Third Coronavirus Response Bill Includes Research Boost
American Institute of Physics ∙ 03/27/2020 ∙ NCATS
Congress Passes COVID-19 Stimulus Bill – Includes Science Funding
The American Society for Cell Biology ∙ 03/27/2020 ∙ NCATS
Astronaut Conducts Heart Research on Station with Former Colleague
National Aeronautics and Space Administration ∙ 03/25/2020 ∙ Tissue Chip
At the Heart of Spaceflight
ISS U.S. National Laboratory ∙ 03/25/2020 ∙ Tissue Chip
Five Language Outcome Measures Evaluated for Intellectual Disabilities Studies
UC Davis Health ∙ 03/24/2020 ∙ CTSA Program
E-Cigarette Users Had Substances Linked to Bladder Cancer in Urine, Review Finds
UNC Lineberger Comprehensive Cancer Center ∙ 03/19/2020 ∙ CTSA Program
C-Path Receives FDA Grant to Establish Rare Disease Clinical Outcome Assessment Consortium
Arizona Bioindustry Association ∙ 03/19/2020 ∙ Rare Diseases
Having a Low Birthweight Baby May Increase Risk for Early Heart Failure
American College of Cardiology ∙ 03/18/2020 ∙ NCATS
Two-Step Method Patches Herniated Discs
Cornell University ∙ 03/11/2020 ∙ CTSA Program
Irregular Sleep Patterns May Raise Risk of Heart Disease
NIH Research Matters ∙ 03/10/2020 ∙ NIH
Blood Platelets Trigger Events that Cause Organ Damage After Heart Surgery
Duke University Health System ∙ 03/09/2020 ∙ CTSA Program
Arming the Body’s Immune Cells
University of Cincinnati ∙ 03/09/2020 ∙ CTSA Program
Cancerous Tumors, Surrounding Cells Illuminated by New Imaging Agent
Washington University School of Medicine ∙ 03/09/2020 ∙ CTSA Program
New Paper Describes Accurate, Scalable Method for Detecting Fragile X Syndrome in Newborns
RTI International ∙ 03/05/2020 ∙ CTSA Program
Newfound Cell Defense System Features Toxin-Isolating ‘Sponges’
NYU Langone Health ∙ 03/04/2020 ∙ CTSA Program
Little Tissue, Big Mission: Beating Heart Tissues to Ride Aboard The ISS
Johns Hopkins University ∙ 03/04/2020 ∙ Tissue Chip
People with MS Are Living Longer. How Does Neurodegeneration in These Patients Change as They Age?
University at Buffalo ∙ 03/04/2020 ∙ CTSA Program
Device Helps Deliver Electronic Cigarette Vapors for Research
Penn State ∙ 03/04/2020 ∙ CTSA Program
Despite Best Intentions, Researchers Don’t Always Share Findings with Study Participants
Medical University of South Carolina ∙ 03/02/2020 ∙ CTSA Program
Memory Concerns? Blood Test May Put Mind at Ease or Pave Way to Promising Treatments
University of California, San Francisco ∙ 03/02/2020 ∙ RDCRN

February 2020

Seven Questions for a Rare Disease Warrior
NIH Director’s Blog ∙ 02/27/2020 ∙ Rare Diseases
Mortality Decreased among People with Opioid Use Disorder who Receive Further Treatment After Detox
Boston Medical Center ∙ 02/25/2020 ∙ CTSA Program
BioUtah and the University of Utah’s TVC Announce Startups Chosen to Pitch at the 2020 Entrepreneur & Investor Life Science Summit
BioUtah ∙ 02/24/2020 ∙ NCATS, SBIR/STIR
Media Advisory: NIH-Funded Effort May Help People with Intellectual Disability Participate in Clinical Studies
NCATS, NICHD ∙ 02/24/2020 ∙ CTSA Program
Diabetes in Mice Cured Rapidly Using Human Stem Cell Strategy
Washington University School of Medicine ∙ 02/24/2020 ∙ CTSA Program
A Cancerous Conversation Fuels Oral Tumors
NCATS, NIDCR ∙ 02/18/2020 ∙ ExRNA
Activity Tracker Data May Help Improve Flu-like Outbreak Predictions
NIH Office of Behavioral and Social Sciences Research ∙ 02/18/2020 ∙ CTSA Program
Kebotix, NCATS Collaborate to Deliver New Treatments for Diseases Faster
Kebotix, Inc. ∙ 02/12/2020 ∙ NCATS
Novel Melatonin Receptor Molecules Make Possible Therapies That Adjust Biological Clocks to Our Environments
University at Buffalo ∙ 02/10/2020 ∙ CTSA Program
U-M Team Targets Muscular Dystrophy in Mice
University of Michigan ∙ 02/07/2020 ∙ Rare Diseases
NIH Holds Inaugural Seminar on American Rural Health
NIH Record ∙ 02/07/2020 ∙ CTSA Program

January 2020

Genetic Testing in Diverse Young Breast Cancer Patients over a Decade
Florida Atlantic University ∙ 01/28/2020 ∙ CTSA Program
BPA Exposure in Pregnancy Affects Genes Related to Obesity and Diabetes
The Children’s Hospital of Philadelphia ∙ 01/28/2020 ∙ CTSA Program
Micro-Scaled Method Holds Promise for Cancer Diagnosis
Baylor College of Medicine ∙ 01/27/2020 ∙ CTSA Program
Study Examines Reliability of Biopsies from Donated Kidneys Prior to Transplantation
American Society of Nephrology ∙ 01/23/2020 ∙ CTSA Program
Teens with Obesity and PCOS Have More "Unhealthy" Bacteria
Endocrine Society ∙ 01/23/2020 ∙ CTSA Program
Study Finds Link between Blood Fats, Artery Size in MS Patients
University at Buffalo ∙ 01/22/2020 ∙ CTSA Program
Adrenaline Handbrake
Harvard Medical School ∙ 01/22/2020 ∙ CTSA Program
Changing Cancer Care, One Organoid at a Time
Wake Forest Baptist Medical Center ∙ 01/21/2020 ∙ CTSA Program
Insurance Status Helps Explain Racial Disparities in Cancer Diagnosis
NIH Director’s Blog ∙ 01/21/2020 ∙ CTSA Program
Statewide Autism Study Finds Later Diagnoses for Girls, High Rates of Co-Occurring Disorders
Brown University ∙ 01/20/2020 ∙ CTSA Program
Walnuts May Be Good for the Gut and Help Promote Heart Health
Penn State ∙ 01/16/2020 ∙ CTSA Program
Study Challenges Concerns over Hospital Readmission Reduction Practices
The University of Texas Southwestern Medical Center ∙ 01/15/2020 ∙ CTSA Program
Study Finds Novel Molecular Therapeutic Target for Colon Cancer
Boston University School of Medicine ∙ 01/14/2020 ∙ CTSA Program
Racial Disparities in Heart Failure Explained
The University of Texas Southwestern Medical Center ∙ 01/14/2020 ∙ CTSA Program
Are Racial/Ethnic Disparities in Breast Cancer Diagnosis Caused by Health Insurance Coverage?
The ASCO Post ∙ 01/14/2020 ∙ CTSA Program
Researchers Find Clues to Drug Resistance in Medulloblastoma Subtype
University of North Carolina at Chapel Hill School of Medicine ∙ 01/13/2020 ∙ CTSA Program
New Tests May Help Diagnose Rare Subset of Eosinophilic Disorders
Cincinnati Children's Hospital Medical Center ∙ 01/06/2020 ∙ RDCRN
Center for Health Equity Transformation Seeks to Improve Health of All Kentuckians
University of Kentucky, Center for Clinical and Translational Science ∙ 01/02/2020 ∙ CTSA Program
Duke Researchers Garner Over $6 Million in NIH Funding to Fight Genetic Diseases
Duke University, Pratt School of Engineering ∙ 01/02/2020 ∙ Somatic Cell Genome Editing

December 2019

The Making of a Neuroscientist
Global Genes ∙ 12/24/2019 ∙ RDCRN
UK College of Pharmacy Researchers Uncover New Biomarker for Cardiovascular Disease
University of Kentucky, Center for Clinical and Translational Science ∙ 12/19/2019 ∙ CTSA Program
A Country-Spanning Cancer Collaboration: Scientific Team-Up Identifies Source of Tumor Drug Resistance
NIH Intramural Research Program ∙ 12/17/2019 ∙ Chemistry Technology
Mayo Clinic Researchers Look at Post Menopause as Key Factor in Endometrial Cancer
Mayo Clinic ∙ 12/16/2019 ∙ CTSA Program
Zooming in on Brain Circuits Allows Researchers to Stop Seizure Activity
Georgetown University ∙ 12/16/2019 ∙ CTSA Program
The Foundation of Modern Chemistry and Beyond
The University of North Carolina at Chapel Hill ∙ 12/16/2019 ∙ Biomedical Data Translator
Saliva Test Shows Promise for Earlier and Easier Detection of Mouth and Throat Cancer
Elsevier ∙ 12/13/2019 ∙ ExRNA
Scientists Discover Key Neural Circuit Regulating Alcohol Consumption
UNC Health Care and UNC School of Medicine ∙ 12/10/2019 ∙ CTSA Program
Verantos Receives a Grant from the National Institutes of Health (NIH) to Fund Advanced Clinical Phenotyping in Real World Evidence Studies
PR Newswire ∙ 12/10/2019 ∙ SBIR/STIR
Improvements Needed for Hepatitis C Testing in Youth
Boston Medical Center ∙ 12/10/2019 ∙ CTSA Program
Brain Function Irregular in Children with Type 1 Diabetes, Study Says
Stanford Medicine ∙ 12/09/2019 ∙ CTSA Program
FDA Launches App for Health Care Professionals to Report Novel Uses of Existing Medicines for Patients with Difficult-to-Treat Infectious Diseases
Food and Drug Administration ∙ 12/05/2019 ∙ New Therapeutic Uses
Researchers Find Common Measures of Immune Status, Inflammation Can Predict Mortality
Cleveland Clinic ∙ 12/02/2019 ∙ CTSA Program
Translational Research Framework Gains a Following
NIEHS ∙ 12/01/2019 ∙ CTSA Program

November 2019

Organ Transplant Candidates with Prostate Cancer Diagnosis May Not Need to Delay Transplantation
The University of Chicago Medical Center ∙ 11/26/2019 ∙ CTSA Program
High-Throughput Screening IDs Drug Pair That Fights Deadly Childhood Tumor
Stanford Medicine ∙ 11/20/2019 ∙ Chemistry Technology
Popular Electronic Cigarette May Deliver Nicotine More Effectively than Others, Researchers Say
Penn State College of Medicine ∙ 11/15/2019 ∙ CTSA Program
Newly Identified Flu Antibodies Could Improve Vaccines and Treatments
NIH Research Matters ∙ 11/05/2019 ∙ CTSA Program
Gene-Editing Advance Puts More Gene-Based Cures Within Reach
NIH Director’s Blog ∙ 11/05/2019 ∙ Somatic Cell Genome Editing

October 2019

Dare to Dream: The Long Road to Targeted Therapies for Cystic Fibrosis
NIH Director’s Blog ∙ 10/31/2019 ∙ CTSA Program
UI Team Is Developing New Delivery Tools for Gene Editing
University of Iowa, Carver College of Medicine ∙ 10/31/2019 ∙ Somatic Cell Genome Editing
Many Take Anticoagulants and OTC Supplements, which Poses Risk
University of California, Los Angeles ∙ 10/31/2019 ∙ CTSA Program
iTHRIV CTSA Scholar Program Now Accepting Applications
Virginia Polytechnic Institute and State University ∙ 10/30/2019 ∙ CTSA Program
CCTS Data Warehouse Supports Award-Winning Research on Impact of Employer-Sponsored Community Supported Agriculture
University of Kentucky, Center for Clinical and Translational Science ∙ 10/30/2019 ∙ CTSA Program
Rare Kidney Diseases Receive Third Round of Funding
Patient Worthy ∙ 10/28/2019 ∙ Rare Diseases
$5M in Federal Funding to Help Patients with Urea Cycle Disorders
Children's National Hospital ∙ 10/24/2019 ∙ RDCRN
One Little Girl’s Story Highlights the Promise of Precision Medicine
NIH Director’s Blog ∙ 10/23/2019 ∙ CTSA Program
Funding from NIH, U-M, and NephCure International to Support Research of Major Cause of Rare Kidney Diseases
University of Michigan ∙ 10/23/2019 ∙ RDCRN
Three Leading Children’s Hospitals Will Expand Genomic Research Network with New NIH Grant
The Children’s Hospital of Philadelphia ∙ 10/23/2019 ∙ CTSA Program
NIH National Center for Advancing Translational Science: Involving Rural America in Research
Rural Health Information Hub ∙ 10/23/2019 ∙ CTSA Program
UK, UAB Study Shows Metformin Offers No Strength Training Benefits for Seniors
University of Kentucky, Center for Clinical and Translational Science ∙ 10/22/2019 ∙ CTSA Program
New CRISPR Genome Editing System Offers a Wide Range of Versatility in Human Cells
Broad Institute ∙ 10/21/2019 ∙ Somatic Cell Genome Editing
Professors Kam Leong and Elisa Konofagou Win $3.2 M NIH Award to Advance Genome Editing
Columbia University in the City of New York ∙ 10/21/2019 ∙ Somatic Cell Genome Editing
NIH Funding Supports Rare Diseases Research Collaborations
Federal Laboratory Consortium for Technology Transfer ∙ 10/16/2019 ∙ RDCRN
High Levels of Chronic Stress Linked to High Blood Pressure in African Americans
American Heart Association ∙ 10/16/2019 ∙ CTSA Program
Mayo Researcher Secures NIH Grant to Advance Care of Rare Disease
Mayo Clinic Center for Individualized Medicine ∙ 10/15/2019 ∙ RDCRN
If at First You Don’t Succeed, Try, Try Again: An Improved Strategy to Treat Itch
International Association for the Study of Pain ∙ 10/15/2019 ∙ ADST
Hillstream BioPharma Announces Renewal of CRADA with National Center for Advancing Translational Sciences for Use of QUATRAMER™ Drug Delivery Technology with HDAC6-PI3Kδ Dual Inhibitor for AML
Hillstream BioPharma ∙ 10/10/2019 ∙ NCATS
NIH Awards $7.5 Million to Ramp Up Clinical Trials for Rare, Genetic Airway Diseases
University of North Carolina at Chapel Hill School of Medicine ∙ 10/09/2019 ∙ RDCRN
CReATe Consortium Aims for ALS Breakthroughs with NIH Renewal Grant
University of Miami Miller School of Medicine ∙ 10/04/2019 ∙ RDCRN
NIH Grant to Support a Multi-Center Initiative to Advance Research, Treatment for Leukodystrophies
Children’s Hospital of Philadelphia ∙ 10/03/2019 ∙ RDCRN
NIH Grant Funds Brittle Bone Disorder Consortium
Baylor College of Medicine ∙ 10/03/2019 ∙ RDCRN
$28M Grant Funds Cincinnati Children’s as Coordinating Center for Rare Diseases Research Network
Cincinnati Children's Hospital Medical Center ∙ 10/03/2019 ∙ RDCRN
OHSU Leads New Rare Disease Consortium
Oregon Health & Science University ∙ 10/03/2019 ∙ RDCRN
Exploring Autism by way of Three Rare Genetic Disorders
Boston Children’s Hospital ∙ 10/03/2019 ∙ RDCRN
CMU and Yale Receive NIH Grant to Further Gene Editing Technique
Carnegie Mellon University ∙ 10/03/2019 ∙ Somatic Cell Genome Editing
Genome Editing To Be Tested in Kidney Organoids
University of Washington School of Medicine ∙ 10/01/2019 ∙ Somatic Cell Genome Editing
Funding: NIH Grant Supports Genome Editing Cancer Immunotherapy Research
Western University, Schulich School of Medicine & Dentistry ∙ 10/01/2019 ∙ Somatic Cell Genome Editing
Dahlman and Santangelo Awarded $3.5M NIH Grant to Develop a New mRNA-based Drug that Corrects DNA in Genes
Georgia Tech ∙ 10/01/2019 ∙ Somatic Cell Genome Editing
UC Davis Awarded New CRISPR Grant to Test Novel Approach to Cancer Treatment
UC Davis Comprehensive Cancer Center ∙ 10/01/2019 ∙ Somatic Cell Genome Editing

September 2019

NIH HEAL Initiative Issues Awards to UB Researchers to Develop Non-Addictive Painkillers
University at Buffalo ∙ 09/30/2019 ∙ HEAL
Body-on-a-Chip Device Predicts Cancer Drug Responses
NIH Director’s Blog ∙ 09/26/2019 ∙ Tissue Chip
Hesperos Human-on-a-Chip Technology Awarded First Phase of $3.8 Million Milestone-based NIH Grant to Study Opiate Overdoses in Collaboration With UCF
Hesperos, Inc. ∙ 09/26/2019 ∙ Tissue Chip
Kidney Tissue Chips in Space: Opportunities and Challenges
ISS U.S. National Laboratory ∙ 09/20/2019 ∙ Tissue Chip
Building Risk Prediction Models for Type 2 Diabetes Using Machine Learning Techniques
Centers for Disease Control and Prevention ∙ 09/19/2019 ∙ CTSA Program
New Purdue AI Tech to Track Treatment of Chronic Stomach Disease
Purdue University ∙ 09/19/2019 ∙ SPARC
Gene Editing Enables Researchers to Correct Mutation in Muscle Stem Cells in Muscular Dystrophy Mouse Model
University of Missouri School of Medicine ∙ 09/17/2019 ∙ TRND
Nano-Sized Solution for Efficient and Versatile CRISPR Gene Editing
NIH Director’s Blog ∙ 09/17/2019 ∙ Somatic Cell Genome Editing
Tiny Capsules Packed with Gene-Editing Tools Offer Alternative to Viral Delivery of Gene Therapy
University of Wisconsin–Madison ∙ 09/09/2019 ∙ Somatic Cell Genome Editing
AI to Help Prevent Heart Failure
Federal Telemedicine News ∙ 09/09/2019 ∙ CTSA Program
Player Athleticism Increases Head Impact Exposure in Youth Football
Wake Forest Baptist Medical Center ∙ 09/05/2019 ∙ CTSA Program
Researchers Find Alarming Risk for People Coming Off Opioids
Washington University School of Medicine ∙ 09/05/2019 ∙ CTSA Program
NIH’s National Center for Advancing Translational Sciences and Elsevier Strike Agreement for Use of NCATS’ Rare Disease Database to Support Primary Care
Elsevier ∙ 09/04/2019 ∙ GARD
Uncovering a Hidden Zika Outbreak in Cuba
NIH Director’s Blog ∙ 09/03/2019 ∙ CTSA Program

August 2019

How the Trial Innovation Network Helped this Investigator Redesign her Study Proposal to do More Science with Less Money
sc-ctsi.org ∙ 08/28/2019 ∙ CTSA Program
Elderly Have Poor Prognosis After Recovery in Long-Term Acute Care Hospitals
University of California, San Francisco ∙ 08/26/2019 ∙ CTSA Program
Study Uncovers a Strategy That Viruses Use to Evade Immediate Immune Responses
U.S. Naval Research Laboratory ∙ 08/22/2019 ∙ NCGC
Electronic Records Pin Broad Set of Health Risks on Genetic Premutation
University of Wisconsin–Madison ∙ 08/21/2019 ∙ CTSA Program
REDCap Data Management Tool Reaches Million User Mark
Vanderbilt University Medical Center ∙ 08/15/2019 ∙ CTSA Program
Compound Reduces Chronic Itch in Mice
NIH Research Matters ∙ 08/13/2019 ∙ ADST
Dementia Care Program Improves Mental Health of Patients, Caregivers
University of California, Los Angeles ∙ 08/13/2019 ∙ CTSA Program
From Sustaining a Concussion to Conducting Groundbreaking Brain Injury Research
University of Rochester Medical Center ∙ 08/07/2019 ∙ CTSA Program
Single Brain Region is Key to Assessing the Impact of Repetitive Head Hits, Concussions
University of Rochester Medical Center ∙ 08/07/2019 ∙ CTSA Program
Capes, Coloring Books Welcome Littlest ‘Research Rangers’
University at Buffalo ∙ 08/05/2019 ∙ CTSA Program
iTHRIV, Community Groups Partner to Improve Health of Virginians
Virginia Tech ∙ 08/02/2019 ∙ CTSA Program