Open Small Business Opportunities


Grants

Commercialization Readiness Pilot (CRP) Program Technical Assistance

  • SBIR/STTR: PAR-19-334 (SB1, R44 - Clinical Trial Not Allowed)
  • Posted: Aug. 5, 2019
  • Next deadline: Sept. 5, 2019

Methods to Improve Reproducibility of Human iPSC Derivation, Growth and Differentiation

  • SBIR: RFA-GM-19-001 (R44 - Clinical Trial Not Allowed)
  • Posted: May 21, 2019
  • Next deadline: Jan. 6, 2020

PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications

  • STTR: PA-19-270 (R41/R42 - Clinical Trial Not Allowed)
  • Posted: May 7, 2019
  • Next deadline: Sept. 5, 2019
  • STTR: PA-19-271 (R41/R42 - Clinical Trial Required)
  • Posted: May 7, 2019
  • Next deadline: Sept. 5, 2019
  • NOT-AT-19-025: Notice of Special Interest for Small Business Research for Methods Development in Natural Products Chemistry
  • Posted: Aug. 6, 2019
     
  • SBIR/STTR: NOT-OD-19-127 Notice of Special Interest: Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Applications Directed at the Adoption of the Fast Healthcare Interoperability Resources (FHIR) Standard
  • Posted: July 30, 2019

See: Additional Resources: 2019 SBIR/STTR Omnibus Solicitation Resources

PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications

  • SBIR: PA-19-272 (R43/R44 - Clinical Trial Not Allowed)
  • Posted: May 7, 2019
  • Next deadline: Sept. 5, 2019
  • SBIR: PA-19-273 (R43/R44 - Clinical Trial Required)
  • Posted: May 7, 2019
  • Next deadline: Sept. 5, 2019
  • NOT-AT-19-025: Notice of Special Interest for Small Business Research for Methods Development in Natural Products Chemistry
  • Posted: Aug. 6, 2019
     
  • SBIR/STTR: NOT-OD-19-127 Notice of Special Interest: Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Applications Directed at the Adoption of the Fast Healthcare Interoperability Resources (FHIR) Standard
  • Posted: July 30, 2019

See: Additional Resources: 2019 SBIR/STTR Omnibus Solicitation Resources

Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project

  • SBIR: PA-19-034 (R43/R44)
  • Posted: Oct. 4, 2018
  • Next deadline: Sept. 5, 2019
  • STTR: PA-19-033 (R41/R42)
  • Posted: Oct. 4, 2018
  • Next deadline: Sept. 5, 2019

Administrative Supplements to Promote Diversity in Research and Development  Small Businesses-SBIR/STTR 

Development of Highly Innovative Tools and Technology for Analysis of Single Cells

  • SBIR: PA-17-147 (R43/R44)
  • Posted: Feb. 1, 2017
  • Next deadline: Sept. 5, 2019
  • STTR: PA-17-148 (R41/R42)
  • Posted: Feb. 1, 2017
  • Next deadline: Sept. 5, 2019

Platform Delivery Technologies for Nucleic Acid Therapeutics

NIH HEAL InitiativeSM Funding Opportunities

America’s Startups and Small Businesses Build Technologies to Stop the Opioid Crisis

  • SBIR: RFA-DA-19-019
  • Posted: Dec. 10, 2018
  • Next deadline: Sept. 8, 2019
  • STTR: RFA-DA-19-020
  • Posted: Dec. 10, 2018
  • Next deadline: Sept. 8, 2019

Contracts

HHS Small Business Innovation Research (SBIR) Program Contract Solicitation (PHS 2020-1) Now Available

Notices Relevant to Small Businesses

NIH Offers Assistance to Phase II HHS SBIR and STTR Awardees through the NIH Commercialization Accelerator Program (CAP) 2019-2020

NIH Offers Assistance to Active Phase I HHS SBIR and STTR Awardees through the Niche Assessment Program 2018-2019

Notice of NIA Participation in RFA-HL-18-023 "Stimulating Access to Research in Residency (StARR) (R38)"

Notice of Corrected Expiration Date for PA-15-354 "SBIR Technology Transfer (R43/R44)"

NIH Offers Assistance to Active Phase I HHS SBIR and STTR Awardees through the Niche Assessment Program 2017-2018

NIH Implementation of Final Research Performance Progress Reports for SBIR and STTR Grants and Cooperative Agreements

Update on Clinical Trial Funding Opportunity Announcement Policy

ASSIST Now an Option for Small Business Grant Applications

Applicant Responsibilities in Maintaining the Integrity of NIH Peer Review

HHS Changes Standard Due Dates for SBIR/STTR Grant Applications

NIH Implements Option for Applicants to Switch between the SBIR/STTR Programs and the SBIR Direct to Phase II Pilot of the SBIR/STTR Reauthorization Act of 2011

Need Help?

The NCATS SBIR & STTR team is available to answer questions related to your potential project idea and provide tips for applying. If you have questions about a specific solicitation, connect with the program contact listed in the solicitation.

The Small Business Resources page offers tools and tips to help you develop a successful proposal and access other resources.