Translator Projects

With the goal of developing a Biomedical Data Translator to integrate the vast amounts of currently available medical research data and accelerate the development of new treatments, NCATS issued awards to form project teams of experts from different leading universities and research institutions. In the first phase of the program, teams established feasibility, producing new biological insights and identifying novel therapeutic opportunities using a combination of existing literature, experimental characterization and clinical data. Translator awardees are now beginning in earnest to build the tools needed to support the integration of diverse data types and demonstrate the potential impact of mining those integrated data using new analytical tools that promote the discovery of complex relationships between the data for the research community.

A lung-on-a-chip

  

Click the image above to download the Translator process graphic.

Translator Draft Architecture. A researcher will be able to use NCATS Biomedical Data Translator to help answer difficult biomedical questions like, “predict treatments for disease Y.” The query will be sent to Translator’s Autonomous Relay Agents (ARAs) to determine how best to answer the query. The ARA will break the query into smaller tasks that are transmitted to rich, specialty knowledge bases called Knowledge Providers (KPs). This process will be iterative, such that the ARAs and KPs can build on information from the others. Researchers will be able to explore this distilled knowledge and help them to develop new research hypotheses that lead to new scientific discoveries!

Translator Investigators

The following Translator Investigators are grouped by team name.

(im)Prove Agent
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Institute for Systems Biology
University of California San Francisco
Clinical Data Services Provider
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Columbia University
Maastricht University
Connection Hypothesis Provider
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Dartmouth University
Expander Agent
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Institute for Systems Biology
Oregon State University
Pennsylvania State University
Explanatory Agent
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Drexel University
Tufts University
Exploring Agent
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Scripps Research
Exposures Provider
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Renaissance Computing Institute at University of North Carolina, Chapel Hill
Genetics Provider
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Broad Institute
Molecular Data Provider
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Broad Institute
Multiomics Provider
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Institute for Systems Biology
Ranking Agent
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CoVar Applied Technologies
Renaissance Computing Institute at University of North Carolina, Chapel Hill
Service Provider
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Scripps Research
Standards and Reference Implementation
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Lawrence Berkeley National Laboratory
Oregon State University
Renaissance Computing Institute at University of North Carolina, Chapel Hill
Text Mining Provider
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University of Colorado Denver
Unsecret Agent
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University of Alabama at Birmingham

Contact

Translator staff