Andrew C. Patt, Ph.D.
Bioinformatics Scientist
Informatics
Division of Preclinical Innovation
Contractor
Contact Info
Biography
Andrew C. Patt, Ph.D., is a bioinformatics scientist in the Informatics Core of NCATS’ Division of Preclinical Innovation. He develops and maintains software, including:
- MetLinkR (a tool for standardizing and linking metabolite names)
- RaMP-DB (a database of functional annotations for metabolites and genes)
- FLIPRTools (a tool for screening compounds using the FLIPR calcium channel assay)
- DTSEA (a tool for identifying novel drug target combinations from high-throughput screening data)
Patt earned his doctorate in biomedical science from The Ohio State University in 2021. He also holds a Bachelor of Science in biochemistry with a minor in biomathematics from SUNY–Geneseo.
Research Topics
Patt uses his bioinformatics and biostatistics expertise for various -omics and compound screening efforts both within the Informatics Core and across NCATS.
Selected Publications
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Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage
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MDM2-Dependent Rewiring of Metabolomic and Lipidomic Profiles in Dedifferentiated Liposarcoma Models
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Exploring NCATS In-House Biomedical Data for Evidence-Based Drug Repurposing
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Metabolomics and Multi-Omics Integration: A Survey of Computational Methods and Resources
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Integration of Metabolomics and Transcriptomics to Identify Gene-Metabolite Relationships Specific to Phenotype