NCATS supports innovative research in biology and spurs advances in drug discovery by investing in the development of new chemistry technologies. Center experts in this discipline work on varied projects that address fundamental problems in molecular biology and the drug discovery process.
NCATS supports chemical technologies ranging from novel small molecule library design to inventive bioanalytical techniques. Explore selected chemistry technology projects below:
- Development of a Novel Inhibitor of Fumarate Hydratase in Mycobacterium Tuberculosis
- Development of a Small Molecule Inhibitor of the ß-O-Linked-N-Acetylglucosamine Transferase (OGT)
- Development of an Activator of the Pyruvate Kinase Isoform M2 (PKM2)
- Development of Dual-Acting IRAK/Fit3 Inhibitors for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS)
- Development of the αllbß3 Antagonist RUC-4 for the Treatment of Myocardial Infarction (MI) and Congestive Heart Failure
- Development of (2R,6R)-Hydroxynorketamine as a Treatment for Depression