CTSA Program Funding Information

The CTSA Program provides critical resources and support needed to strengthen the entire spectrum of our nation’s clinical and translational research enterprise. CTSA Program hubs provide core resources, essential mentoring and training, and opportunities to develop innovative approaches and technologies designed to re-engineer existing capabilities. Program support also fosters collaborations to improve the quality, safety, efficiency and speed of clinical and translational research.

Funded Activities Under the CTSA Program

The CTSA Program receives appropriated funds, as part of the annual fiscal year appropriation to NCATS, and uses these funds to support several programs, initiatives, and activities. View a table of CTSA Program - Funded Activities (PDF - 110.31KB).

In addition, due to the success and demonstrated impact of the CTSA program, funds from other sources have been provided to the CTSA Program to leverage the program’s expertise and resources. These other funds do not offset the existing NCATS appropriated funds and do not add to the NCATS annual base funding of the program. View a table of CTSA Program - Funding from Other Sources (PDF - 96.24KB).

Current Funding Announcements

NCATS has released the following funding opportunity announcements for the CTSA Program.

Clinical and Translational Science Awards

  • PAR-21-121: Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
  • PAR-18-940: Clinical and Translational Science Award (U54 Clinical Trial Optional)
    • NOT-TR-20-036: Notice of Change to Key Dates for PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
    • NOT-TR-19-014: Notice of Change to PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
      • NOT-TR-19-026: Notice of Change to NOT-TR-19-014: Notice of Change to PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
    • NOT-TR-19-013: Notice of Change to PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
    • NOT-TR-19-010: Notice of Change to PAR-18-940 Clinical and Translational Science Award (U54 Clinical Trial Optional)
    • CTSA Program PAR-18-940 Application Information

Consortium Centers

  • PAR-21-203: Limited Competition: Clinical and Translational Science Awards (CTSA) Consortium-Wide Centers: Resources for Rapid Demonstration and Dissemination (U24 Clinical Trials Not Allowed)
    • NOT-TR-21-025: Notice of Special Interest (NOSI): Topic Areas for PAR-21-203, Limited Competition: Clinical and Translational Science Award (CTSA) Consortium-Wide Centers: Resources for Rapid Demonstration and Dissemination (U24 Clinical Trials Not Allowed)

Collaborative Innovation Awards

  • Collaborating, Implementing and Dissemination Innovations in Clinical and Translational Science Research – Application Information
  • NOT-TR-20-007: Notice of Special Interest: Research through NCATS’ Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Awards (U01 and R21)
  • PAR-19-099: Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Award (U01 Clinical Trial Optional)
    • NOT-TR-20-004: Notice of Change to Award Budget and Removal of Prior Approval Requirement for PAR-19-099, Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Award (U01 Clinical Trial Optional)
    • NOT-TR-19-023: Notice of Change to PAR-19-099 Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Award (U01 Clinical Trial Optional)
    • NOT-TR-19-016: Notice of Change to FOA PAR-19-099: Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Award (U01 Clinical Trial Optional)
  • PAR-19-100: Limited Competition: Clinical and Translational Science Award (CTSA) Program: Exploratory Collaborative Innovation Awards (R21 Clinical Trial Optional)
    • NOT-TR-19-024: Notice of Change to PAR-19-100 Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative Innovation Award (R21 Clinical Trial Optional)
    • NOT-TR-19-017Notice of Change to FOA PAR-19-100: Limited Competition: Clinical and Translational Science Award (CTSA) Program: Exploratory Collaborative Innovation Awards (R21 Clinical Trial Optional)

Administrative Supplements

  • NOT-TR-21-017: Notice of Special Interest (NOSI): Administrative Supplements for the Clinical and Translational Science Award (CTSA) Program to Address COVID-19 Public Health Needs
  • NOT-TR-21-011: Notice of Special Interest (NOSI): Availability of Emergency Administrative Supplements to Clinical and Translational Science Award (CTSA) Program Awards to Address 2019 Novel Coronavirus Disease (COVID-19) Public Health Needs
  • PA-21-071: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)
  • PA-20-272: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
  • NOT-OD-21-001: Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program KL2 Institutional Career Development Awards as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project
  • NOT-OD-20-024: Notice of Special Interest (NOSI): Availability of Administrative Supplements for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down Syndrome) Project
  • NOT-AT-20-010: Notice of Special Interest: NCCIH Administrative Supplements to NCATS CTSA Programs for Scholars Pursuing Complementary Health Research Career Development
  • NOT-TR-20-014: Notice of Special Interest: Clinical and Translational Science Award (CTSA) Program Administrative Supplements
  • PA-18-592: Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed)

Conference Grants

View all of NCATS’ current funding opportunities.

Notices

  • NOT-TR-21-026: Notice of Information: Change in NCATS Prior Approval Process for New CTSA Program Pilot Projects and KL2 Projects that Involve Human Subjects Research
  • NOT-TR-21-024: Notice of Information: NCATS to Issue an Emergency Competitive Revision Sole Source Award in Support of ACTIV-6
  • NOT-TR-21-022: Notice of Special Interest (NOSI): Availability of Emergency Competitive Revisions for the Clinical and Translational Science Award (CTSA) Program to Address COVID-19 Public Health Needs
  • NOT-TR-20-019: Notice of Information: Change in NCATS Prior Approval Process for New CTSA Program Pilot Projects that Involve Human Subjects Research
  • NOT-TR-19-015: Notice of Information: NCATS Clinical and Translational Science Awards (CTSA) Programs Interest in Improving Rural Health Outcomes and Eliminating Health Disparities
  • NOT-TR-18-025: National Center for Advancing Translational Sciences (NCATS) Policy for Support of Phase III Clinical Trial Activities for a Rare Disease or Condition

View all of NCATS’ current notices.

Expired Funding Announcements

Visit the expired CTSA Program funding announcements page to learn more about past CTSA Program funding opportunities.