CTSA Program Funding Information

Latest Updates

New NOT-TR-23-007: Notice of Information: NCATS Prior Approval Process for New CTSA Program UM1 and K12 Scholar Projects that Involve Human Subjects Research
New NOT-TR-23-005: Notice of Termination for PAR-22-122: Limited Competition: Clinical and Translational Science Awards (CTSA) Consortium-Wide Centers: Resources for Rapid Demonstration and Dissemination (U24 Clinical Trials Optional)
New NOT-TR-23-003: Notice of Special Interest (NOSI): Research through NCATS Clinical and Translational Science Award (CTSA) Program: High Impact Specialized Innovation Programs (RC2)
New NOT-TR-23-002: Notice of Termination for NOT-TR-22-023 NCATS Notice of Special Interest (NOSI): Research through NCATS Clinical and Translational Science Award (CTSA) Program: High Impact Specialized Innovation Programs (RC2)
New NOT-TR-22-037: Notice of Change in Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program PAR-21-337 (T32 Clinical Trial Not Allowed)
New NOT-TR-22-035: Notice of Change in Eligibility for CTSA Program Funding Opportunities: PAR-21-336 (K12), PAR-21-339 (R25), PAR-21-338 (T32), and PAR-21-337 (T32)
New NOT-OD-22-192: Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program KL2/K12 Institutional Career Development Awards as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project
New NOT-OD-22-191: Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program T32/TL1 Institutional Training Program as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project

The CTSA Program provides critical resources and support needed to strengthen the entire spectrum of our nation’s clinical and translational research enterprise. CTSA Program hubs provide core resources, essential mentoring and training and opportunities to develop innovative approaches and technologies designed to re-engineer existing capabilities. Program support also fosters collaborations to improve the quality, safety, efficiency and speed of clinical and translational research.

Funded Activities Under the CTSA Program
Current Funding Announcements
Notices
Related Opportunities of Interest
Guidance
Expired Funding Announcements

Funded Activities Under the CTSA Program

As part of its annual fiscal year appropriation, NCATS receives funds to support the programs, initiatives and activities of the CTSA Program. Each CTSA-funded institution provides core resources, subject-matter expertise, and training and educational opportunities to support clinical and translational science. Together, these institutions work collaboratively, as part of the CTSA national network, to address significant challenges and opportunities to advance biomedical research into health solutions. With the demonstrated success and impact of the CTSA Program, NCATS has leveraged the expertise and resources of CTSA Program, resulting in additional funding from sources beyond NCATS’ appropriation. These other funds do not offset the existing NCATS appropriated funds and do not add to the NCATS annual base funding of the program. View a table of CTSA Program Funded Activities and Other Sources (PDF - 178.8KB).

Current Funding Announcements

NCATS has released the following funding opportunity announcements for the CTSA Program.

Clinical and Translational Science Awards

PAR-21-340: Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science for UM1 CTSA Hub Awards (RC2 Clinical Trials Not Allowed)
- RC2 Overview
  - Download slides (PDF - 383.6KB)
- New NOT-TR-23-003: Notice of Special Interest (NOSI): Research through NCATS Clinical and Translational Science Award (CTSA) Program: High Impact Specialized Innovation Programs (RC2)
- New NOT-TR-23-002: Notice of Termination for NOT-TR-22-023 NCATS Notice of Special Interest (NOSI): Research through NCATS Clinical and Translational Science Award (CTSA) Program: High Impact Specialized Innovation Programs (RC2)
PAR-21-293: Clinical and Translational Science Award (UM1 Clinical Trial Optional)
- CTSA Program Summary Data Guide
- CTSA Program UM1 Budget Request Tables
- Overview Diagram of the Application Elements
- Application Information
- Technical Assistance Webinar:
  - Introduction
    - Download slides (PDF - 903.5KB)
  - UM1 Overview
    - Download slides (PDF - 432.9KB)
  - UM1 Live Q&A
PAR-21-121: Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)

Research Training and Career Development Awards

PAR-21-339: Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)
PAR-21-338: Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
PAR-21-337: Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
- New NOT-TR-22-037: Notice of Change in Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program PAR-21-337 (T32 Clinical Trial Not Allowed)
PAR-21-336: Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)
Application Information for CTSA Program Research Training and Career Development Awards
- Technical Assistance Webinar
  - Introduction
  - K12 Overview
    - Download slides (PDF - 1.1MB)
  - T32 Postdoctoral Overview
    - Download slides (PDF - 542.4KB)
  - T32 Predoctoral Overview
    - Download slides (PDF - 297.3KB)
  - R25 Overview
    - Download slides (PDF - 1.1MB)
      Note: R25 Overview begins on slide 33.

Consortium Centers

PAR-22-122: Limited Competition: Clinical and Translational Science Awards (CTSA) Consortium-Wide Centers: Resources for Rapid Demonstration and Dissemination (U24 Clinical Trials Optional)
- NOT-TR-23-005: Notice of Termination for PAR-22-122: Limited Competition: Clinical and Translational Science Awards (CTSA) Consortium-Wide Centers: Resources for Rapid Demonstration and Dissemination (U24 Clinical Trials Optional)

Collaborative Innovation Awards

PAR-22-167: Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)
- Collaborating, Implementing and Dissemination Innovations in Clinical and Translational Science Research – Application Information

Administrative Supplements

New NOT-OD-22-192: Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program KL2/K12 Institutional Career Development Awards as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project
New NOT-OD-22-191: Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program T32/TL1 Institutional Training Program as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project
New NOT-OD-22-137: Notice of Special Interest (NOSI): Availability of Administrative Supplements for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project
NOT-TR-21-022: Notice of Special Interest (NOSI): Availability of Emergency Competitive Revisions for the Clinical and Translational Science Award (CTSA) Program to Address COVID-19 Public Health Needs
NOT-TR-21-017: Notice of Special Interest (NOSI): Administrative Supplements for the Clinical and Translational Science Award (CTSA) Program to Address COVID-19 Public Health Needs
PA-20-272: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Research Supplements to Promote Diversity, Re-entry and Reintegration into Health-Related Research Careers

NOT-OD-21-134: Research Supplements to Promote Re-entry and Reintegration into Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed)
PA-21-071: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)
- CTSA Program Diversity, Re-entry and Reintegration Supplements
  - See: CTSA Program-Specific Guidance for Diversity and Re-entry Research Supplements

Conference Grants

Conference grants supported with funding from the CTSA Program must:

be from a primary CTSA institution or a CTSA partnering institution (see list on the CTSA Program UM1 Budget Request Tables page,
address the CTSA Program goals (listed on the About the CTSA Program page), and
have consortium-wide impact and/or are intended for participation by multiple CTSAs.

CTSA supported conference grants must comply with NCATS-specific Conference Grant Information.

View all of NCATS’ current funding opportunities.

Notices

New NOT-TR-23-007: Notice of Information: NCATS Prior Approval Process for New CTSA Program UM1 and K12 Scholar Projects that Involve Human Subjects Research
NOT-TR-21-026: Notice of Information: Change in NCATS Prior Approval Process for New CTSA Program Pilot Projects and KL2 Projects that Involve Human Subjects Research
NOT-TR-19-015: Notice of Information: NCATS Clinical and Translational Science Awards (CTSA) Programs Interest in Improving Rural Health Outcomes and Eliminating Health Disparities
NOT-TR-18-025: National Center for Advancing Translational Sciences (NCATS) Policy for Support of Phase III Clinical Trial Activities for a Rare Disease or Condition
NOT-OD-15-014: Reminder: NIH Requires the Research Performance Progress Report (RPPR) for All Type 5 Progress Reports (Updated RPPR guidance for CTSA Program hubs [download a copy to access the appendices]: 2023 Supporting Instructions for CTSA Program RPPRs – RELEASED SEPTEMBER 2022 [654KB - PDF] and view RPPR FAQs.)

View all of NCATS’ current notices.

Related Opportunities of Interest

PA-21-345: Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)

Guidance

Expired Funding Announcements

Visit the expired CTSA Program funding announcements page to learn more about past CTSA Program funding opportunities.