CTSA Program Projects & Initiatives

Streamlined, Multisite, Accelerated Resources for Trials Institutional Review Board 

To streamline the institutional review board (IRB) process for multisite clinical research, NCATS is supporting the development of the Streamlined, Multisite, Accelerated Resources for Trials (SMART) IRB Platform. SMART IRB is a single IRB reliance platform for multisite clinical studies, enabling study sites to rely on a single IRB of record. Learn more about the SMART IRB.

Trial Innovation Network

The Trial Innovation Network is a new collaborative initiative composed of three key organizational partners: three Trial Innovation Centers, a Recruitment Innovation Center and the CTSA Program hubs. NCATS’ vision for the Trial Innovation Network is to address critical roadblocks in clinical trials and to accelerate the translation of novel interventions into life-saving therapies. Learn more about the Trial Innovation Network.

CTSA Program Collaboration Innovation Awards

CTSA Program Collaborative Innovation Awards (CCIA) are intended to foster research collaboration by encouraging teams from three or more CTSA Program hubs to work together to develop, demonstrate and disseminate innovative, experimental approaches to overcoming translational science roadblocks. Learn more about the CTSA Program CCIA.

Common Metrics Initiative 

The Common Metrics Initiative is designed to assess and optimize the CTSA Program’s overall impact on the nation’s health. Establishing a set of standard evaluation measures across CTSA Program hubs helps focus program activities, streamline data collection, and demonstrate measurable progress toward program goals, including improvements in research translation and workforce development. Learn more about the Common Metrics Initiative.

National Center for Data to Health

Through the National Center for Data to Health (CD2H), informatics experts are using CTSA Program resources to develop standardized approaches and best practices that address operational and institutional barriers to sharing data. The CD2H aims to help make data more meaningful, open and accessible, a key goal in NCATS’ efforts to improve translational science. Learn more about the CD2H.

CTSA Program Rural Health Efforts

Rural Americans, who make up about one fifth of the U.S. population, face numerous health challenges including higher rates of poverty, fewer healthcare specialists, high rates of risk behaviors, and remote locations that make it difficult to access care. Due to the CTSA Program’s nationwide reach and ability to foster diverse collaborations and engage communities, funded investigators are uniquely positioned to support interventions that improve health in rural America. Learn more about these efforts.