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7530 NCATS Day Poster: CTSA Program Patient and Community Engagement   Download the poster here. CTSA Program Patient and Community Engagement CTSA Program Patient and Community Engagement
7529 NCATS Day Poster: NCATS Division of Clinical Innovation   Download the poster here. Division of Clinical Innovation Division of Clinical Innovation
7487 NCATS Day Poster: Drug Combination Discovery at NCATS   Download the poster here. Drug Combination Discovery at NCATS Drug Combination Discovery at NCATS
7486 NCATS Day Poster: Assay Development & Screening Technology   Download the poster here. Assay Development & Screening Technology Assay Development & Screening Technology
7473 NCATS Day 2017 Posters ​NCATS Day included a poster session that showcased the Center's research and activities. View the posters below. Assay Development & Screening Technology Biomedical Data Translator CTSA Program Patient and Community Engagement Division of Clinical Innovation Drug Combination Discovery at NCATS Genetic and Rare Diseases Information Center NCATS Chemical Genomics Center NCATS Therapeutic Development Branch: TRND & BrIDGs ​NCATS Toolkit for Patient-Focused Therapy Development Project New Therapeutic Uses Program Office of Strategic Alliances Rare Diseases Clinical Research Network Stem Cell Translation Laboratory The Trans-NIH RNAi Facility Tissue Chip for Drug Screening Program Trial Innovation Network NCATS Day 2017 Posters NCATS Day 2017 Posters
7472 NCATS Day 2017 Presentations ​NCATS Day featured a wide range of presentations about many of the programs and initiatives that NCATS offers. View the presentations below. NCATS Day - Partnering with Patients for Smarter Science (PDF - 266KB) Case Study in Translational Science Collaboration (PDF - 273KB) Biomedical Data Translator (PDF - 167KB) Clinical and Translational Science Awards Program (PDF - 217KB) NCATS Division of Preclinical Innovation (PDF - 69KB) New Therapeutic Uses Program (PDF - 68KB) Office of Rare Diseases Research (PDF - 388KB) Office of Strategic Alliances (PDF - 68KB) Therapeutics for Rare and Neglected Diseases & Bridging Interventional Development Gaps (PDF - 378KB) Tissue Chips for Drug Screening (PDF - 333KB) NCATS Day 2017 Presentations NCATS Day 2017 Presentations
7471 NCATS Day 2018 NCATS is committed to including diverse patient and community perspectives in all phases of translational science, from basic research to public health implementation. To facilitate and advance robust dialogue and meaningful collaboration, NCATS staff hosted NCATS Day 2018: Engaging Patients and Communities for Smarter Science on the NIH main campus in Bethesda, Maryland, on Sept. 28, 2018. Purpose NCATS Day 2018: Engaging Patients and Communities for Smarter Science provided a forum to share and reflect upon patient and community needs — as well as best practices in addressing those needs — so that the Center can best shape its research priorities, programs and initiatives. Patients and patient advocates, caregivers, community partners, community health engagement professionals, clinical and translational researchers, NCATS staff and others shared and discussed ways to overcome translational research challenges and leverage opportunities through effective patient and community engagement. Participants learned strategies to broaden participation in research and to incorporate patient and community input in their work. (Daniel Soñé Photography) 2018 Event Information Sept. 28, 2018 8:30 a.m. - 5 p.m. National Institutes of Health William H. Natcher Building (Building 45) Natcher Conference Center, Rooms E1/E2 45 Center Drive Bethesda, Maryland 20892 This full-day event featured presentations, interactive discussion and activities, and a poster session. The event fostered an open dialogue for participants to discuss common roadblocks to translational science, brainstorm ideas for improvement and apply that knowledge to strengthen patient and community engagement at NCATS.  Website • Agenda (PDF - 36KB) • Videocast  • Photos • Participant Roster (PDF - 847KB) • Community Engagement Resources • Patient Engagement Resource (PDF - 421KB) • Posters • NCATS Fact Sheet (PDF -351KB) (Daniel Soñé Photography) Who Should Attend NCATS encourages the following groups to participate: Patients, patient advocates and caregivers Community members and representatives Community health engagement professionals Clinical and translational researchers NCATS staff Past Events View the presentations, posters and photos from NCATS Day 2017. /sites/default/files/ncats-day-900.jpg NCATS Day /sites/default/files/ncats-day-900.jpg NCATS Day
7394 News Brief: NCATS Supports Novel Methods to Improve Institutional Review Board Efficiencies Kim Shoenbill, a Ph.D. student in the clinical investigation program at the University of Wisconsin Institute for Clinical and Translational Research, used machine learning and statistical methods to analyze institutional review board review times for a quality improvement study. University of Wisconsin Institute for Clinical and Translational Research Photo. NCATS’ Clinical and Translational Science Awards Program support helped a University of Wisconsin–Madison Ph.D. student discover new ways of identifying factors affecting institutional review board (IRB) review times. The results, recently published in the Journal of Clinical and Translational Science, can serve as a guide to improve IRB efficiencies. Posted July 2017 NCATS' CTSA Program support helped a University of Wisconsin–Madison Ph.D. student discover new ways of identifying factors affecting institutional review board (IRB) review times /sites/default/files/wisconsin-kimberly.jpg NCATS Supports Ways to Improve Institutional Review Board Efficiencies NCATS' CTSA Program support helped a University of Wisconsin–Madison Ph.D. student discover new ways of identifying factors affecting institutional review board (IRB) review times /sites/default/files/wisconsin-kimberly.jpg NCATS Supports Ways to Improve Institutional Review Board Efficiencies
7393 NCATS Stem Cell Translation Laboratory Grand Opening On July 6, 2017, NCATS officially opened its Stem Cell Translation Laboratory (SCTL), which is supported through the NIH Common Fund. SCTL scientists are seeking proposals to collaborate on projects to bring pluripotent stem cell technology closer to clinical application, drug discovery and regenerative medicine. Learn more about stem cell research at NCATS.  NCATS Stem Cell Translation Laboratory Grand Opening NCATS Stem Cell Translation Laboratory Grand Opening
7386 News Brief: CTSA Program Mentoring Helps Engineers Develop Innovative Rehabilitation Therapies Michael Fu, Ph.D. (left), and Jayme Knutson, Ph.D. (right), with their Contralaterally Controlled Functional Electrical Stimulation video game therapy, an innovative method for training hand function in adults after stroke and in children with cerebral palsy. Erika Woodrum/Cleveland Functional Electrical Stimulation Center Photo. After completing a Ph.D. in electrical engineering at Case Western Reserve University, Michael Fu wanted to use his skills in medical robotics to solve problems in rehabilitation medicine and focus on helping patients recover in their homes. The challenge was that he didn’t have experience in clinical research or working with patients. Fu found a solution through the Mentored Clinical Research Scholars (KL2) program at the Case Western Clinical and Translational Science Collaborative in Cleveland. Supported by NCATS’ Clinical and Translational Science Awards (CTSA) Program, the KL2 program enables early-stage investigators to conduct team-based clinical research and helps them jumpstart independent careers in translational research. “The most valuable parts of the program included the formulation of a plan to develop my clinical research skills and the mentors who were willing to train me on the clinical side,” said Fu. For example, he learned how to design and carry out clinical trials to test whether the devices he created helped patients. He also worked with a transdisciplinary team of researchers, physicians, physical therapists and patients while developing and testing the device. “I was able to bounce ideas off the people who assign the therapies and the patients who will use the therapy,” Fu said. “It allowed me to see the whole continuum of the translation spectrum and understand the big picture.”  Through the program, Fu connected with former KL2 scholar Jayme Knutson, Ph.D., associate professor in the Department of Physical Medicine and Rehabilitation at Case Western Reserve University and MetroHealth Medical Center in Cleveland. Knutson was working on a promising new electrical stimulation device to help stroke patients regain control of their paralyzed or weak hand. Patients wear a glove with sensors on their unaffected hand. When they open their unaffected hand, the device sends electrical stimulation to the paralyzed hand that causes it to open. The device is unique because it enables patients to control the stimulation themselves and allows them to use their hand to practice tasks, leading to better results than with other electrical stimulation therapies. Fu was impressed — especially since patients could use the device in their own homes — but Knutson wanted to make the therapy more engaging. With KL2 program support and mentoring from Knutson, Fu created video games to use with the device, including a skee ball game where opening the weak hand launches the ball. Getting patients to adhere to their rehabilitation therapy is a major challenge. But the patients Knutson and Fu worked with found the games were fun, which might help them stick with therapy. Additionally, the video game encourages patients to not just open and close their weak hand but also control how wide they open it in order to achieve a task on the screen. This could help re-train the brain better than electrical stimulation therapy alone, something Knutson and Fu are studying. Both Fu and Knutson credit the KL2 program with getting this innovative therapy off the ground and launching their careers as independent investigators. As a KL2 program scholar, Fu tested the video game-assisted electrical stimulation therapy in a small sample of children with cerebral palsy and found that it helped them. Based on these promising results, Fu, who is now an assistant professor in the Department of Electrical Engineering and Computer Science at Case Western Reserve University, received independent funding to test the therapy in a larger clinical trial of cerebral palsy patients. Fu and Knutson recently received a grant from the New England Pediatric Device Consortium to commercialize their device. But they know their work will not be done until the device gets to market. “The last thing a biomedical engineer wants to do is to develop a therapy that can help people but then never makes it out of the lab and into the hands of those who need it,” said Knutson.   Posted July 2017 NCATS-supported KL2 program enables early-stage investigators to conduct team-based clinical research and helps them jumpstart independent careers in translational research. /sites/default/files/case-western_900.jpg CTSA Program Mentoring Helps Engineers Develop Rehabilitation Therapy NCATS-supported KL2 program enables early-stage investigators to conduct team-based clinical research and helps them jumpstart independent careers in translational research. /sites/default/files/case-western_900.jpg CTSA Program Mentoring Helps Engineers Develop Rehabilitation Therapy

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