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We offer an array of funding opportunities that support our mission of turning research observations into health solutions through translational science.

Open Funding Opportunities

Find an open funding opportunity using the search tool. The expiration date currently displayed is the final expiration date.

Learn more about the NIH clinical trial requirements for grants and contracts.

If you are looking for closed opportunities, visit grants.nih.gov.

Investigators may apply for NIH-funded scientific conference grants to support high-quality national and international meetings that are relevant to public health and our mission. See NIH’s frequently asked questions for more information.

Name NCATS Issued FOA Number Activity Code Posting Date Expiration Date Opportunity Type
Notice of Extension of the Response Date for NOT-TR-20-010, Announcement of the NCATS Rare Diseases Are Not Rare! Challenge Prize Competition ✔ NOT-TR-20-021 04/13/2020 Notice of Change to Funding Opportunity
Announcement of the NCATS Rare Diseases Are Not Rare! Challenge Prize Competition ✔ NOT-TR-20-010 02/19/2020 Notice of Information
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed) ✔ RFA-TR-23-016 R21 07/05/2023 03/24/2024 NA
Notice of Participation of the National Center for Advancing Translational Sciences (NCATS) in RFA-HL-20-014 - "Rare Disease Cohorts in Heart, Lung, Blood and Sleep Disorders (UG3/UH3 Clinical Trial Not Allowed)" ✔ NOT-TR-19-022 06/05/2019 Notice of Change to Funding Opportunity
Notice of Change to PAR-18-953 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed) ✔ NOT-TR-19-012 10/29/2018 NA
Notice of Change to PAR-18-952 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed) ✔ NOT-TR-19-011 10/29/2018 NA
Announcement of the NCATS Rare Diseases Are Not Rare! Challenge ✔ NOT-TR-19-002 09/26/2018 NA
Notice of Modification to RFA-TR-18-020 Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional) ✔ NOT-TR-18-030 07/23/2018 NA
Notice of Pre-Submission Webinars for RFA-TR-18-020: Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional) and RFA-TR-18-021: Data Management and Coordinating Center (DMCC) ✔ NOT-TR-18-029 06/19/2018 NA
Notice of NCATS Participation in RFA-HL-19-018 NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional) ✔ NOT-TR-18-026 05/16/2018 NA
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Last updated on June 12, 2026