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Small Business Funding

Our SBIR and STTR programs provide technical assistance and funding opportunities to help small business and research organizations advance technologies and research concepts that can eventually be commercialized to improve health.

About Small Business Funding



Learn More Small Business Facts

Download the SBIR & STTR fact sheet

There are two primary SBIR and STTR funding mechanisms: grants and contracts. We also support other programs that work with small businesses to advance technology products. View all small business funding opportunities from NCATS.

SBIR & STTR Grants

Omnibus Solicitation

Applications due: Jan. 5, April 5 and Sept. 5

The annual SBIR/STTR Omnibus Solicitation encourages investigator-initiated grant applications across a broad range of research areas. Eligible U.S. small businesses should have the capabilities and technological expertise to contribute to the research and development missions of the awarding NIH institute or center. Small businesses interested in NCATS funding should review our research priorities prior to applying. The typical award date is six to nine months after the submission of a successful application.

Targeted Grant Funding Announcements

Applications due: Varies

Throughout the year, NCATS may release funding opportunities or participate in other NIH grant funding announcements to advance technologies in a targeted area.

Support Programs

Varying support programs (i.e., administrative supplement awards) are offered to active SBIR/STTR awardees, all of which have varying application periods and deadlines. For NCATS participation in a program or supplement, please contact your program officer or refer to the active funding announcement.

SBIR & STTR Contracts

Applications due: Typically in the fall

We accept applications for SBIR contract funding once each year. Contract topics cover a wide range of technology development areas to help successfully finance and advance innovations toward commercialization. Applicants should review the contract topic areas above and submit a proposal related to one of those topics. Applicants are encouraged to contact the NCATS SBIR & STTR teamfor more information about our contract topics of interest.

Additional Resources for Small Businesses

NCATS SBIR and STTR awardees may be eligible for support beyond funding, including access to small business resources.

See our resources: