NCATS is looking for innovative partners to join its dynamic team. Learn more about current job opportunities at NCATS or across NIH and the Department of Health and Human Services (HHS). NIH and HHS are Equal Opportunity Employers.
Deputy Director, National Center for Advancing Translational Sciences
NCATS seeks exceptional candidates for the position of Deputy Director. The individual selected for this position will work closely with the NCATS Director to provide leadership in catalyzing the creation, demonstration and dissemination of innovative methods and technologies that enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. As one of the National Institutes of Health Institutes/Centers, NCATS works to speed the translational science process from basic discovery to better diagnostics and new treatments.
Applicants must possess a Ph.D., M.D., or equivalent doctorate degree in the biomedical sciences, with broad senior-level research experience and experience in direct administration of a research program and expert scientific knowledge in the broad fields of biomedical, clinical and translational research. Applicants should be known and respected within their profession, both nationally and internationally, as distinguished individuals of outstanding scientific competence and administrative capability.
Candidates should have demonstrated leadership abilities, the ability to serve as a spokesperson, experience with planning, executing, and assessing complex multifaceted preclinical and clinical programs, particularly those utilizing NIH extramural mechanisms. Experience is also required in the resolution of operational problems and issues, as well as demonstrated ability to manage financial and human resources including building, motivating and maintaining a culturally diverse staff.
The Deputy Director, NCATS, will be appointed at a salary commensurate with his/her qualifications and experience. Full Federal benefits, including leave, health and life insurance, long-term care insurance, retirement, and savings plan (401K equivalent) will be provided.
Applicants must submit a current CV and bibliography electronically to Mr. Will Hennings at SeniorRe@od.nih.gov, or for questions call 301-402-7227. In addition, applicants also must submit a supplemental narrative statement that addresses the qualifications requirements (not to exceed two pages) and a supplemental narrative statement that addresses how they envision supporting NCATS’ vision for advancing its translational science mission (not to exceed two pages). Applications must be received by 11:59 p.m. ET on Tuesday, June 5, 2018. For more information, view the full vacancy announcement.
Supervisory Informatics Scientist
NCATS seeks applications from exceptional informatics scientists to serve as the informatics program lead in the Division of Pre-Clinical Innovation (DPI). DPI studies translation of basic discoveries into tangible improvements to human health at a systems level as a scientific and operational problem. The scientists within DPI come from a broad range of scientific disciplines – including, among others, therapeutic discovery, preclinical development, toxicology, biomarkers and clinical application – to reduce, remove or bypass significant bottlenecks across the entire continuum of translation and to train the future translational science workforce.
The incumbent will serve as the informatics program lead for NCATS intramural research. The leader sets the informatics research agenda, leading a diverse team of data science, bioinformatics, cheminformatics and software development professionals with discovery, preclinical development and clinical repurposing expertise to advance NCATS translational science initiatives. The position requires a strong interdisciplinary foundation in therapeutic development, genomics, mathematics, and algorithm and informatics platform development. The leader should have a strong record of high-impact publications and experience providing tools and resources to the broader research community. The informatics program lead will be accountable for project planning, execution and project completion, serving as a point person responsible for advancing collaborative projects through milestone-driven project areas.
Applicants must possess biomedical research or informatics training with a doctoral degree (M.D., Ph.D. or equivalent) and a record of accomplishment in preclinical translation with demonstrated experience working with multidisciplinary research teams in technology and therapeutic/diagnostic/intervention development. The ideal candidate will be an internationally recognized and highly accomplished researcher in data science, clinical informatics, bioinformatics or cheminformatics and familiar with all aspects of preclinical translation, with specific interest and accomplishments in novel technology and paradigm development. He or she must have expertise and accomplishment in multiple aspects of preclinical translation from target validation through early development of therapeutics and/or diagnostics to proof-of-concept in humans, and broad and first-hand knowledge of the field of rare disease therapeutic development, including small molecule, biologic and gene-therapy approaches. The candidate must have demonstrated experience working with scientifically diverse research programs, with administrative and interpersonal skills to lead a diverse workforce and to provide research and program direction. The individual must have the ability to influence, inspire and empower scientists and administrative staff to be creative, self-motivated, entrepreneurial achievers who deliver on the mission of the organization through individual and collaborative initiative. Finally, he or she must be a collaborative leader with demonstrated experience in engaging a broad range of stakeholders, such as scientists from different disciplines, patient advocacy groups, government agencies and other nonprofit organizations. Open to both U.S. citizens and non-U.S. citizens.
The current salary range is commensurate with experience and accomplishments; a full civil service package of benefits (including retirement, health, life and long-term care insurance, Thrift Savings Plan participation, etc.) is available.
Please submit a cover letter describing your interest in the position, including a career synopsis (1-3 pages); statement of research interests (1-2 pages); a current curriculum vitae and complete bibliography; and the names and contact information of three references to NCATSSSRecruit@mail.nih.gov. Application packages will only be accepted electronically. The position will remain open until filled.
All information provided by candidates will remain confidential and will not be released outside the NCATS search process without a signed release from candidates. The NIH encourages the application and nomination of qualified women, minorities and individuals with disabilities. DHHS and NIH are Equal Opportunity Employers.
The NCATS Informatics group seeks a self-motivated, collaborative research scientist to join its programs, studying therapeutic translation on a system-wide level as a scientific and operational problem. The candidate will develop research and methods in the areas of target prioritization, therapeutic drug discovery, knowledge representation, recommendation algorithms, network modeling and inference, and the quantitative analysis of the bottlenecks in translation. The Center convenes expert teams from diverse scientific disciplines — including, among others, therapeutic discovery preclinical development, toxicology, biomarkers and clinical application — to reduce, remove or bypass significant bottlenecks across the entire continuum of translation and to train the future translational science workforce. The candidate is expected to assess the current research program and take on projects related to the Center’s mission and provide guidance where required to the other members of the program.
While the candidate is expected to have significant expertise in therapeutic drug discovery, cheminformatics, machine learning and other relevant topics in molecular informatics, experiences in additional areas of informatics (bioinformatics, text mining, image analytics, etc.) are desirable. More important than any specific expertise is the ability to address problems across different domains and bring to bear the relevant expertise when necessary. A fundamental requirement is a high degree of proficiency in at least one programming language — such that writing code and manipulating data do not create a bottleneck when tackling problems.
While a key goal for this position is to develop and implement informatics research, in the context of translational science, the candidate is also expected to support day-to-day operations as needed. This could range from advising on good statistical practice to munging unusual file formats.
The candidate is expected to actively disseminate his or her own work through publications, presentations at national and international conferences and via the open sharing of tools and source code. Given the collaborative nature of NCATS, the candidate will be collaborating with other groups within NCATS and is encouraged to develop collaborations outside the Center as well. There will be opportunities to work with experimental scientists so that novel methods can be tested on real data.
The NCATS Informatics group plays a key role in the operation of multiple screening platforms (small molecules, RNAi, ADME, drug combinations) and large-scale infrastructure within the Division of Preclinical Innovation at NCATS. Informatics scientists are committed to research and development in all areas of molecular informatics. The group provides an intellectually stimulating environment and is interested in a diverse range of informatics topics that vary in scale from small molecules to phenotypes and other high-level biomedical datatypes. We collaborate with academic, government and commercial computational and experimental groups throughout the world.
Applicants must possess a Ph.D. in an informatics-related discipline or equivalent; he or she must have strong programming skills – ideally in R. If not, he or she should have experience with other data analysis environments (Python, Matlab, etc). In general, the informatics scientist likely will need to munge internal and external data. Applicants also must possess strong oral and written English communication skills. A background in biology (ideally in proteins and networks) is preferred, as are experience in therapeutic drug discovery or preclinical development; experience with Bayesian networks; experience with text mining/modeling; experience with Java development, and a track record of sharing tools, code and resources with the broader research community.
Please submit a cover letter describing your interest in the position, current curriculum vitae and complete bibliography (all in PDF format) to Noel Southall (firstname.lastname@example.org).
Postdoctoral Positions in the Division of Pre-Clinical Innovation
The Division of Pre-Clinical Innovation (DPI) is the intramural (i.e., on-site) research program of NCATS and is located in Rockville, Maryland, a few miles from the main NIH campus in Bethesda, Maryland. DPI focuses on early stages of the translational process, from target validation to first-in-human studies. More than 200 scientists from a variety of disciplines and across the spectrum from early-career scientists to senior leaders are responsible for advancing the diverse research portfolio of DPI. In addition to conducting cutting-edge laboratory research, DPI scientists collaborate with more than 250 research organizations worldwide.
DPI scientists work in a collaborative, team-based environment. The postdoctoral candidate will be recruited to work on the specific projects described below and will have ample opportunities to collaborate with scientists both within and outside of NCATS on additional projects. Candidates are expected to present results of ongoing work at meetings (such as internal group meetings and national conferences) and submit their work for publication in scientific journals. Postdoctoral fellows also gain additional professional skills and exposure to a variety of career paths through participation in the DPI training program.
Stem Cell Scientist and Postdoctoral Positions, Division of Pre-Clinical Innovation
NCATS seeks applications from qualified candidates with expertise in the biology of human embryonic and induced pluripotent stem cells (iPSCs) to join the Center’s newly established stem cell program. Candidates with a strong background in cell, molecular and systems biology also are encouraged to apply.
The selected candidates will join a multidisciplinary team of innovative scientists with expertise in assay development, high-throughput and -content screening, compound management, automation engineering, bioinformatics, medicinal chemistry and various “-omics” technologies. They will work in a highly creative environment, focusing on important aspects of human pluripotency and cellular differentiation using cutting-edge technologies (e.g., single-cell analysis, deep sequencing, automated cell culture, high-throughput electrophysiology). The selected candidates also will establish new standards, quality controls, improved differentiation protocols and other resources for the iPSC field. They will be responsible for conducting research and advancing specific programs in coordination with the stem cell team leader.
The ideal candidates will be expected to work independently as well-trained problem solvers in pluripotent stem cell biology and iPSC technology. They will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained. They also will draft technical reports, manuscripts and patent applications and present work internally and externally to consultants and collaborators as needed.
Each applicant must possess an advanced degree (M.D. and/or Ph.D.) in a relevant field. Exceptional candidates with master’s degrees and strong backgrounds in stem cell biology will be considered. Candidates with experience in drug discovery, cell and tissue engineering, cell signaling or quantitative biology are encouraged to apply. The ideal candidates should be team players with high scientific standards and have the ability to work in an interactive, fast-paced environment. They must be self-motivated to learn new technologies and be familiar with the methods and concepts of stem cell biology and regenerative medicine.
Interested individuals should send a cover letter, a curriculum vitae with a bibliography and the contact information of at least three references to NCATSstemcellhiring@mail.nih.gov.
Review of applications will begin immediately and continue until positions are filled.