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Malaria Drug Combination Data Release

NCATS researchers tested thousands of drug combinations to identify potential treatments for malaria.

Work with Us

NCATS' combination screening platform experts regularly collaborate with basic researchers and clinical investigators inside and outside the National Institutes of Health on an as-needed basis.

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Matrix Combination Screening

NCATS experts use a technology called matrix combination screening to quickly narrow down a long list of potential drug combinations and find those with the most potential to help patients. Learn more.

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About Matrix Combination Screening

Find out more about matrix combination screening and the goals for this work at NCATS.

    Scientific Capabilities

    Discover details about the robotic combination screening platform that forms the foundation of this innovative approach.

    Matrix Screening Method

    Learn more about the steps in this NCATS-developed screening method to help identify the best potential drug combinations.

      Work with Matrix Screening

      Find out how basic researchers and clinical investigators can collaborate with NCATS experts for matrix screening.

        A New Way to Test Promising Drug Combinations

        Often, current medical treatments for a variety of diseases — including cancer, tuberculosis and brain disorders — involve administering more than just one drug, an approach known as combination therapy. Thousands of approved and investigational drugs can be combined in millions of possible pairings and dose variations. Clinicians often must make decisions based on trial and error, which is not optimal for the patient or the clinician. Learn more about how NCATS is addressing this critical challenge.