Scientific Publications
NCATS-supported scientists engage in cutting-edge research across the translational science spectrum. Explore the latest advances made possible by NCATS support.
Scientific Publications
Use the filter and search feature below to find recent scientific publications on NCATS-supported research.
Protein Phosphatase 1 Regulatory Subunit PNUTS Prevents CENP-A Mislocalization and Chromosomal Instability
Functional Genomics Laboratory - April 24, 2025 - Molecular and Cellular Biology
Read PublicationHigh-Throughput Screening Identifies Aurora Kinase B as a Critical Therapeutic Target for Merkel Cell Carcinoma
Functional Genomics Laboratory - February 12, 2025 - Nature Communications
Read PublicationFlap Endonuclease 1 Repairs DNA-Protein Cross-Links via ADP-Ribosylation-Dependent Mechanisms
Functional Genomics Laboratory - January 10, 2025 - Science Advances
Read PublicationDistinct Effects of Sacituzumab Govitecan and Berzosertib on DNA Damage Response in Ovarian Cancer
Functional Genomics Laboratory - October 29, 2024 - iScience
Read PublicationDNAJC9 Prevents CENP-A Mislocalization and Chromosomal Instability by Maintaining the Fidelity of Histone Supply Chains
Functional Genomics Laboratory - June 1, 2024 - The EMBO Journal
Read PublicationAKT1 Interacts With DHX9 to Mitigate R Loop-Induced Replication Stress in Ovarian Cancer
Functional Genomics Laboratory - March 15, 2024 - Cancer Research
Read PublicationGenome-Wide High-Throughput RNAi Screening for Identification of Genes Involved in Protein Production
Functional Genomics Laboratory - January 1, 2024 - Methods in Molecular Biology
Read PublicationBLM Overexpression as a Predictive Biomarker for CHK1 Inhibitor Response in PARP Inhibitor-Resistant BRCA-Mutant Ovarian Cancer
Functional Genomics Laboratory - June 21, 2023 - Science Translational Medicine
Read PublicationThe Histone H3/H4 Chaperone CHAF1B Prevents the Mislocalization of CENP-A for Chromosomal Stability
Functional Genomics Laboratory - May 15, 2023 - Journal of Cell Science
Read PublicationScaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk With AKT Signaling
Functional Genomics Laboratory - April 1, 2023 - Molecular Cancer Research
Read PublicationEtoposide-Induced DNA Damage Is Increased in p53 Mutants: Identification of ATR and Other Genes That Influence Effects of p53 Mutations on Top2-Induced Cytotoxicity
Functional Genomics Laboratory - February 14, 2022 - Oncotarget
Read PublicationGenome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for PMP22 Gene-Dosage Disorder Drug Discovery
Functional Genomics Laboratory - June 10, 2021 - ACS Pharmacology & Translational Science
Read PublicationSLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243
Functional Genomics Laboratory - June 1, 2021 - Cancer Research
Read PublicationA High-Throughput Genome-Wide RNAi Screen Identifies Modifiers of Survival Motor Neuron Protein
Functional Genomics Laboratory - May 11, 2021 - Cell Reports
Read PublicationSLFN11 Promotes CDT1 Degradation by CUL4 in Response to Replicative DNA Damage, While its Absence Leads to Synthetic Lethality With ATR/CHK1 Inhibitors
Functional Genomics Laboratory - February 9, 2021 - Proceedings of the National Academy of Sciences of the United States of America
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