N3C Long COVID Tenant

The N3C Long COVID Tenant is a partnership among many organizations to provide clinical data to improve our knowledge and potential treatment strategies.

The Tenant’s data represent millions of patients who were tested or given a positive diagnosis from every state and nearly every county in the nation. The tenant’s size and scope help to ensure public health answers benefit all Americans and their communities.

Partners include the following:

• Health care providers that provide the data in N3C, including institutions supported by the NCATS Clinical and Translational Science Awards (CTSA) Program as well as the NIH National Institute of General Medical Sciences’ Institutional Development Award Networks for Clinical and Translational Research (IDeA-CTR) Programs, and OCHIN
• NCATS, which provides governance, oversight and the secure research platform that provides a broad set of analysis tools for researchers
• The scientific community and research leaders with data science and clinical expertise who are world class experts in harmonizing and standardizing clinical data so that it can be utilized for cutting edge research across the nation

Making Clinical Data More Available for Research

This Tenant receives patient information from health care institutions across the country – see our up-to-date dashboards for institutional counts. We harmonize data from these institutions into a single standardized format and make them available for researchers and clinicians so that they can study the disease and identify potential treatments. This, like every N3C Tenant, is a secure, cloud-based research environment with a powerful analytics platform. Individual level data cannot be removed from the tenant.

To date, researchers have used the Tenant to reveal risk factors for acute and Long COVID, help clinicians choose the most effective treatments, and highlight the greater hospitalization and mortality risk that the disease poses for rural communities and those who are immunocompromised. Researchers currently are studying the comorbidity of HIV, mortality rates in rural populations, Long COVID and potential treatment strategies.