8219 |
Bridging Interventional Development Gaps (BrIDGs) |
The BrIDGs program assists researchers in advancing promising therapeutic agents through late-stage preclinical development toward an Investigational New Drug (IND) application and clinical testing. Learn more.
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8169 |
Matrix Combination Screening |
NCATS experts use a technology called matrix combination screening to quickly narrow down a long list of potential drug combinations and find those with the most potential to help patients.
A New Way to Test Promising Drug Combinations
Often, current medical treatments for a variety of diseases — including cancer, tuberculosis and brain disorders — involve administering more than just one drug, an approach known as combination therapy. Thousands of approved and investigational drugs can be combined in millions of possible pairings and dose variations. Clinicians often must make decisions based on trial and error, which is not optimal for the patient or the clinician. Learn more about how NCATS is addressing this critical challenge.
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Matrix Combination Screening |
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8168 |
Toxicology in the 21st Century (Tox21) |
Throughout their lives, people are exposed to thousands of chemicals in food, household cleaning products, medicines and the environment. However, scientists know little about the potential of most of these substances being toxic to human health. |
Improving toxicity testing methods to enable faster and more efficient evaluation of chemicals' effects on human health. Learn more. |
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Toxicology in the 21st Century (Tox21) |
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8167 |
Chemistry Technology |
Biomedical research functions at its best when experts in chemistry and biology are working together with a common focus and goals. Innovative chemistry technologies can add unique dimensions to drug discovery models, offering the potential to advance nontraditional clinical tools for studying cellular processes.
NCATS researchers who specialize in chemistry technology aim to solve fundamental problems in molecular biology and drug discovery by supporting innovative projects ranging from novel library design to inventive bioanalysis techniques. Learn more about chemistry technology at NCATS.
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Chemistry technology experts at NCATS develop small molecules and screening approaches that other scientists can use to pursue innovations in therapeutic development. Learn more. |
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Chemistry Technology |
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8137 |
Tissue Chip for Drug Screening |
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The Tissue Chip for Drug Screening program aims to develop bioengineered devices to improve the process of predicting whether drugs will be safe or toxic in humans. Learn more
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Tissue Chip for Drug Screening |
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8136 |
Biomedical Data Translator |
The Translator program is funded through the Cures Acceleration Network (CAN). CAN is designed to advance the development of high-need cures and reduce significant barriers between research discovery and clinical trials. Learn more about the Biomedical Data Translator program.
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8135 |
Therapeutics for Rare and Neglected Diseases (TRND) |
TRND program supports preclinical development of therapeutic candidates intended to treat rare or neglected disorders, with the goal of enabling an Investigational New Drug (IND) application. Learn more.
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TRND program supports preclinical development of therapeutic candidates intended to treat rare or neglected disorders, with the goal of enabling an Investigational New Drug (IND) application |
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Therapeutics for Rare and Neglected Diseases (TRND) |
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8087 |
Stories & Publications |
Discover NCATS' collection of featured research stories and scientific publications, or browse the latest issue of NCATS' e-newsletter.
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8086 |
Clinical and Translational Science Awards (CTSA) Program |
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The CTSA Program is designed to develop innovative solutions that will improve the efficiency, quality and impact of the process for turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public. Learn more.console.log('javascript test');!function(c,h,i,m,p){m=c.createElement(h),p=c.getElementsByTagName(h)[0],m.async=1,m.src=i,p.parentNode.insertBefore(m,p)}(document,"script","https://chimpstatic.com/mcjs-connected/js/users/e06bd55ccbb41f1a362306dff/9c199175ea7b167e2bdb5384e.js"); |
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Clinical and Translational Science Awards (CTSA) Program |
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8084 |
About Translation |
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Translation is the process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public — from diagnostics and therapeutics to medical procedures and behavioral changes.
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Translation is the process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public |
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About Translation |
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