NIH Guide notice NOT-OD-15-014 requires that all grant progress reports for the CTSA Program grant mechanisms be submitted electronically using the Research Performance Progress Report (RPPR) format. Please visit the NIH RPPR page for an overview and technical assistance for preparing and submitting reports.

Note: Download the PDF files below and open them in your computer’s PDF application (e.g., Acrobat Reader) in order to access the appendices attached to the PDF.

Read RPPR guidance for CTSA Program institutions:

• 2025 Supporting Instructions for CTSA Program RPPRs – UM1 (PDF - 595KB) – RELEASED SEPTEMBER 2024 
• 2025 Supporting Instructions for Research Performance Progress Reports (RPPRs) for the Clinical and Translational Science Awards (CTSA) Program UL1, KL2 and TL1 Awards (PDF - 167KB) – RELEASED SEPTEMBER 2024

Follow the NIH instructions in Section 7.4 for the K12 and T32 grant mechanisms. If you would like to use the Appendix 3: Training Progress Report template, you can download it (Word - 43.1KB). Use of the template is not required.

RPPR FAQs

Guidance for Correcting Human Subjects Submission Validation Errors (PDF - 798KB)

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