2020 CCIA Projects
Testing the Effectiveness of the Customized Career Development Platform (CCDP): A Cluster Randomized Trial
University of Pittsburgh
Principal Investigator: Doris M. Rubio, Ph.D.
Grant Number: 1R21TR003094-01
Collaborating Institutions: University of Southern California; University of Pennsylvania; Indiana University
Training Promotoras/Community Health Workers Using Culturally and Linguistically Appropriate Research Best Practices
University of Michigan
Principal Investigator: Susan L. Murphy, Ph.D.
Grant Number: 1U01TR003409-01
Collaborating Institutions: University of California, Davis; University of Florida
- Develop and evaluate a research best practices online course for CHWs.
- Demonstrate the effectiveness of research best practices training for CHWs at community sites.
- Disseminate the course throughout the CTSA consortium and beyond.
Empowering the Participant Voice: Collaborative Infrastructure and Validated Tools for Collecting Participant Feedback to Improve the Clinical Research Enterprise
The Rockefeller University
Principal Investigator: Rhonda G. Kost, M.D.
Grant Number: 1U01TR003206-01
Collaborating Institutions: Duke University; Wake Forest University; University of Rochester; Johns Hopkins University; Vanderbilt University
Harnessing Clinical Genomic Characterization to Accelerate Translational Advances for Patients with Intellectual and Developmental Disabilities
Washington University in St. Louis
Principal Investigator: John N. Constantino, M.D.
Grant Number: 1U01TR002764-01A1
Collaborating Institutions: Harvard Medical School; University of Wisconsin–Madison, Children’s Research Institute; The University of North Carolina at Chapel Hill; University of California, Los Angeles; Albert Einstein College of Medicine; Vanderbilt University Medical Center; University of California, Davis; Baylor College of Medicine; University of Pennsylvania; Johns Hopkins University; University of Washington
- Establish standards for feasible neurobehavioral characterization of IDD patients.
- Integrate phenotypic and clinical genomic characterization of patients to directly promote progress in IDD gene and variant curation.
- Establish an IDD patient registry as an extension of the NCATS Center for Data to Health Initiative.
Collaborative Care Teams for Hospitalized Patients with Opioid Use Disorders: Translating Evidence into Practice
Cedars-Sinai Medical Center (University of California, Los Angeles)
Principal Investigator: Itai Danovitch, M.D., M.B.A.
Grant Number: 1U01TR002756-01A1
Collaborating Institutions: The University of New Mexico; Tufts University; RAND Corporation (Tufts University); Baystate Medical Center/Baystate Health (University of Massachusetts Medical School)
SMART IACUC: A Path to Harmonized Veterinary Multi-Site Trial Review
The Ohio State University
Principal Investigator: Sarah A. Moore, D.V.M., M.S.
Grant Number: 1R21TR003191-01
Collaborating Institutions: Tufts University; University of Missouri; Brigham and Women’s Hospital (Harvard University)
Boston University Center for Molecular Discovery Chemical Library Consortium: Fostering Collaborations Between Chemists and Biologists for Translational Discovery
Principal Investigator: John A. Porco, Ph.D.
Grant Number: 1U01TR002625-01A1
Collaborating Institutions: The University of North Carolina at Chapel Hill; University of California, Los Angeles; The University of Chicago; New York University, Vanderbilt University; University of Notre Dame (Indiana University); University of Massachusetts; NCATS
Feasibility and Safety of Interleukin-1 Blockade to Treat Cardiac Sarcoidosis
Virginia Commonwealth University
Principal Investigator: Antonio Abbate, M.D., Ph.D.
Grant Number: 1R21TR003103-01
Collaborating Institutions: University of Michigan; American Heart Association
Gut Microbiome and Steroid Hormones
Rush University Medical Center
Principal Investigator: Ece A. Mutlu, M.D., M.S., M.B.A.
Grant Number: 1R21TR003105-01A1
Collaborating Institutions: Northwestern University
Gut Microbiota in the Modulation of Outcomes After Liver Transplant
Virginia Commonwealth University
Principal Investigator: Jasmohan S. Bajaj, M.D., M.S.
Grant Number: 1R21TR003095-01A1
Collaborating Institutions: Columbia University
Determining the Acceptability and Feasibility of Mobile-Health Approaches to Gather Clinical Information from Patients at Home Following Hospital Discharge
The University of Iowa
Principal Investigator: Philip M. Polgreen, M.D., M.P.H.
Grant Number: 1R21TR003410-01
Collaborating Institutions: Washington University in St. Louis
- Assess the feasibility of using a mobile health approach to gather clinical data from patients in their homes following discharge from the hospital on OPAT.
- Determine patient and researcher perspectives regarding the utility of our approach.
- Estimate the sample size necessary to power a study to determine the utility of remotely collected patient-reported data for predicting hospital readmissions among patients discharged on OPAT.
Translating Scientific Evidence into Practice Using Digital Medicine and Electronic Patient-Reported Outcomes
Icahn School of Medicine at Mount Sinai
Principal Investigator: Ashish Atreja, M.D., M.P.H.
Grant Number: 1U01TR002997-01A1
Collaborating Institutions: Northwestern University; Cleveland Clinic Lerner College of Medicine (Case Western Reserve University)