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NCATS develops novel approaches to improve the process of joining basic science discoveries with initial testing of therapies in humans.
A team of researchers used organoids — tiny 3-D tissue models of human brain development — to better understand brain infections caused by SARS-CoV-2.
NIH researchers identified five U.S. Food and Drug Administration–approved drugs that help maintain healthy calcium levels in the endoplasmic reticulum and prevent proteins from fleeing, which could point to therapies for many diseases.
Researchers from NCATS and the National Cancer Institute teamed up to identify and test different drug combinations against small cell lung cancer (SCLC).
Creating and testing innovative methods to improve and accelerate the drug development process and find new treatments for patients faster.
Discovering new uses for approved drugs to provide the quickest possible transition from bench to bedside.
Developing better model systems for drug and toxicity testing.
Using state-of-the-art resources to enable the ongoing operation of all NCATS translational research activities.
Improving the Drug Development Process
Testing & Predictive Models
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NCATS preclinical programs and resources focus on key obstacles and inefficiencies in the translational process, overcoming bottlenecks that slow the development of new treatments for patients.
Learn more about how to access NCATS programs and expertise.
Take a video tour of our labs and see firsthand how our researchers work to get more treatments to more patients more quickly.
Learn more about NCATS’ Achievements in Advancing Translational Sciences.
NCATS Programs & Resources Supporting Preclinical Innovation