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Preclinical Innovation

A small protein sitting inside an immune cell docking station causes it to change shape.
Reprogramming Immune Cells to Fight Tumors

Immunotherapy holds immense power in harnessing the body’s immune system to fight diseases. Researchers have shown a novel type of immune therapy can reprogram immune cells to stop tumor growth and kill cancer cells.

Treatment with a compound prevents heart damage in a mouse with muscular dystrophy.
A Multipronged Approach Toward Treating DMD

Scientists discover a one-for-all approach toward lessening the symptoms of Duchenne muscular dystrophy and neurodegenerative diseases using high-throughput screening and a mouse model.

Improving the Drug Development Process

Creating and testing innovative methods to improve and accelerate the drug development process and find new treatments for patients faster.

Repurposing Drugs

Discovering new uses for approved drugs to provide the quickest possible transition from bench to bedside.

Testing & Predictive Models

Developing better model systems for drug and toxicity testing.

Core Technologies

Using state-of-the-art resources to enable the ongoing operation of all NCATS translational research activities.

Improving the Drug Development Process

Creating and testing innovative methods to improve and accelerate the drug development process and find new treatments for patients faster.

Repurposing Drugs

Discovering new uses for approved drugs to provide the quickest possible transition from bench to bedside.

Testing & Predictive Models

Developing better model systems for drug and toxicity testing.

Core Technologies

Using state-of-the-art resources to enable the ongoing operation of all NCATS translational research activities.