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Improving the Drug Development Process

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Natural Products Resource Could Help Researchers Find New Treatments

Canvass, a screening library for natural products, was created by NCATS to uncover the potential medical use of these compounds and enable the creation of new treatments for diseases.

Craig Thomas, Ph.D., views and discusses the results of a drug screen with scientists Michele Ceribelli, Ph.D., and Scott Hoyt, Ph.D.
Potential New Drug Combinations for Childhood Cancers

To help address challenges in treating children with cancer, a team of NCATS researchers is rethinking treatment approaches for several difficult-to-treat childhood cancers.

Target Identification & Validation

Developing new approaches and technologies to identify and validate potential drug targets in a more efficient and predictable way.

Assay Development & Screening

Enhancing testing systems to assess the effects of chemical compounds on cellular, molecular or biochemical processes of interest.

Probe Development & Lead Optimization

Creating probes to investigate biological processes and optimizing them to become potential drug candidates.

Core Technologies

Using state-of-the-art resources to enable the ongoing operation of all NCATS translational research activities.

Target Identification & Validation

Developing new approaches and technologies to identify and validate potential drug targets in a more efficient and predictable way.

Assay Development & Screening

Enhancing testing systems to assess the effects of chemical compounds on cellular, molecular or biochemical processes of interest.

Probe Development & Lead Optimization

Creating probes to investigate biological processes and optimizing them to become potential drug candidates.

Core Technologies

Using state-of-the-art resources to enable the ongoing operation of all NCATS translational research activities.

Work with Us

NCATS pre-clinical programs and resources focus on key obstacles and inefficiencies in the translational process, overcoming bottlenecks that slow the development of new treatments for patients.

Learn more about how to access NCATS programs and expertise.

Learn more about NCATS’ Achievements in Advancing Translational Sciences.

Translational Science Spectrum

Learn more about the science of translation.