Research Activities
Our programs, projects and other research activities tackle ongoing challenges in translational research so that new treatments and other health solutions can reach people faster.
Research Activities at NCATS
Through our research activities, we overcome roadblocks that slow progress on developing treatments for many different diseases and that can lead to inequities in clinical outcomes. Explore the range of initiatives we support at NCATS and beyond.
OpenData Portal
Our OpenData Portal is an open and accessible platform for sharing COVID-19-related drug repurposing data and experiments involving approved drugs.
Platform Vector Gene Therapy (PaVe-GT)
Our pilot project is testing the feasibility of increasing the efficiency of gene therapy clinical trials by using the same gene delivery system and manufacturing methods for multiple gene therapies.
Somatic Cell Genome Editing
We help lead this NIH Common Fund program that aims to create and make available high-quality tools for safe and effective genome editing to decrease the time and cost of creating new therapies.
Stem Cell Translation Laboratory (SCTL)
Our experts develop methods and standards to use stem cell technology (using cells derived from skin or blood) to advance treatment approaches.
Stimulating Peripheral Activity to Relieve Conditions (SPARC)
We help lead this NIH Common Fund program to explore the role of peripheral nerves in controlling the functioning of internal organs through electrical signals.
The Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®
As part of the NIH HEAL Initiative, we are applying our translational science approaches to accelerate the development of new treatments for opioid misuse, addiction and pain management.
Tissue Chip for Drug Screening
This program funds the development and testing of models built from human cells for predicting drug safety and toxicity before clinical testing in people.
Toxicology in the 21st Century (Tox21)
Our experts are part of this federal collaboration that aims to rapidly test whether substances are harmful to people.