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Research Activities

Our programs, projects and other research activities tackle ongoing challenges in translational research so that new treatments and other health solutions can reach people faster.

Research Activities at NCATS

Through our research activities, we overcome roadblocks that slow progress on developing treatments for many different diseases and that can lead to inequities in clinical outcomes. Explore the range of initiatives we support at NCATS and beyond.

Stimulating Peripheral Activity to Relieve Conditions (SPARC)

We help lead this NIH Common Fund program to explore the role of peripheral nerves in controlling the functioning of internal organs through electrical signals.

The Helping to End Addiction Long-termĀ® Initiative, or NIH HEAL InitiativeĀ®

As part of the NIH HEAL Initiative, we are applying our translational science approaches to accelerate the development of new treatments for opioid misuse, addiction and pain management.

Therapeutics for Rare and Neglected Diseases (TRND)

Our experts help move new treatments for rare and neglected diseases through the later stages of drug development by collaborating with external scientists and companies.

Tissue Chip for Drug Screening

This program funds the development and testing of models built from human cells for predicting drug safety and toxicity before clinical testing in people.

Toxicology in the 21st Century (Tox21)

Our experts are part of this federal collaboration that aims to rapidly test whether substances are harmful to people.

Last updated on February 19, 2025