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Research Activities

Our programs, projects and other research activities tackle ongoing challenges in translational research so that new treatments and other health solutions can reach people faster.

Research Activities at NCATS

Through our research activities, we overcome roadblocks that slow progress on developing treatments for many different diseases and that can lead to inequities in clinical outcomes. Explore the range of initiatives we support at NCATS and beyond.

3-D Tissue Bioprinting Program

Our scientists are creating and using 3-D printing techniques to make tissue models that closely resemble the complex structure and organization of our cells.

A Specialized Platform for Innovative Research Exploration (ASPIRE)

Through this program, we are building an end-to-end solution for finding, designing and testing new molecules with the potential to become new treatments.

Antiviral Program for Pandemics (APP)

This multi-agency effort to develop safe and effective oral antiviral medications for future pandemics leverages our in-house drug discovery and development expertise and technologies.

Assay Development and Screening Technology (ADST)

Our scientists explore and develop new ways to quickly test and screen potential drug candidates, often in collaboration with disease foundations.

Bespoke Gene Therapy Consortium (BGTC)

We help lead this public-private partnership program that focuses on developing platforms and standards to speed the development and delivery of gene therapies for rare diseases.

Biomedical Data Translator

This program funds projects that integrate existing medical and biological data from different sources to quickly and easily reveal valuable connections and insights about diseases, including potential treatments.

Chemistry Technology

Our chemistry technology experts develop small molecules and screening methods that can be used by other scientists to drive innovations in therapeutic development.

Clinical and Translational Science Awards (CTSA) Program

This program funds a network of more than 60 leading medical institutions to improve the health of individuals and communities through research, resources and training.

Compound Management

Our compound management team uses sophisticated and automated techniques to supply chemicals for NCATS screening experiments to uncover new treatments for diseases.

Functional Genomics Lab

Our functional genomics experts work with collaborators from across NIH institutes and centers to design and use functional genomics technology to advance drug discovery and knowledge about health and disease.

Illuminating the Druggable Genome (IDG)

We help lead this NIH Common Fund program to study and generate resources on key targets for new therapeutic agents.


This NCATS team works with scientists to make sense of data from large experiments to inform decisions that advance translational research.

Matrix Combination Screening

Our experts use matrix combination screening technology to quickly identify promising drug combinations with the most potential to help patients.

Multidisciplinary Machine-Assisted, Genomic Analysis and Clinical Approaches to Shortening the Rare Diseases Diagnostic Odyssey

This grant program funds the development of innovative approaches for reducing the time it takes to accurately diagnose rare diseases.

National COVID Cohort Collaborative (N3C)

Our national resource of clinical and other data for research is being piloted for additional health conditions.

Last updated on April 19, 2024