Research Activities
Our programs, projects and other research activities tackle ongoing challenges in translational research so that new treatments and other health solutions can reach people faster.
Research Activities at NCATS
Through our research activities, we overcome roadblocks that slow progress on developing treatments for many different diseases and that can lead to inequities in clinical outcomes. Explore the range of initiatives we support at NCATS and beyond.
3-D Tissue Bioprinting Program
Our scientists are creating and using 3-D printing techniques to make tissue models that closely resemble the complex structure and organization of our cells.
Bespoke Gene Therapy Consortium (BGTC)
We help lead this public-private partnership program that focuses on developing platforms and standards to speed the development and delivery of gene therapies for rare diseases.
Biomedical Data Translator
This program funds projects that integrate existing medical and biological data from different sources to quickly and easily reveal valuable connections and insights about diseases, including potential treatments.
Bridging Interventional Development Gaps (BrIDGs)
This in-house program helps researchers in advancing promising therapeutic agents through late-stage preclinical development to clinical testing.
Clinical and Translational Science Awards (CTSA) Program
This program funds a network of more than 60 leading medical institutions to improve the health of individuals and communities through research, resources and training.
Clinical Trial Readiness for Rare Diseases, Disorders and Syndromes (CTR) Grants Program
Through this program, we offer grants for projects focused on collecting data needed to advance promising therapies and diagnostics for rare diseases toward clinical trials.
Gene-Targeted Therapies
We are developing generalizable approaches to advance gene-targeted therapies for many rare diseases.
Informatics
Our team works with scientists to make sense of data from large experiments to inform decisions that advance translational research.
More About Informatics
LitCoin
LitCoin helps the NIH share data by giving researchers a way to get recognized for sharing their data and findings through scientific papers.
Matrix Combination Screening
Our experts use matrix combination screening technology to quickly identify promising drug combinations with the most potential to help patients.
More About Matrix
MMA-101
This project will test a gene therapy as a potential treatment for a rare genetic disorder.
Multidisciplinary Machine-Assisted, Genomic Analysis and Clinical Approaches to Shortening the Rare Diseases Diagnostic Odyssey
This grant program funds the development of innovative approaches for reducing the time it takes to accurately diagnose rare diseases.
More About Multidisciplinary Machine-Assisted, Genomic Analysis
NIH Quantum Biomedical Innovations and Technologies (Qu-BIT) Program
Qu-BIT aims to further the application of innovative novel quantum-enabled sensing technologies and quantum computing approaches for various biomedical and translational use cases purposes.
Platform Vector Gene Therapy (PaVe-GT)
Our pilot project is testing the feasibility of increasing the efficiency of gene therapy clinical trials by using the same gene delivery system and manufacturing methods for multiple gene therapies.
More About the PaVe-GT
Preclinical Chemical Biology Laboratory
Our scientists and collaborators bridge chemistry and the biology underlying disease to develop new ways to discover and create chemical probes and potential drug candidates.