Translational Science Interagency Fellow

Division of Preclinical Innovation
Early Translation Branch
Adenine Team
National Center for Advancing Translational Sciences
National Institutes of Health

Biography

Keyla Tumas, Ph.D.

Keyla Tumas completed her postdoctoral training as a Translational Science Interagency Fellow (TSIF) from 2021 to 2024 under the mentorship of Anton Simeonov. Ph.D. (National Center for Advancing Translational Science, National Institutes of Health, NCATS/NIH) and Noel Southall, Ph.D., Heather Stone, M.P.H. and Leonard Sacks, M.D., (United States Food and Drug Administration, FDA), on the project “Repurposing for Neglected Infectious Diseases.”

Tumas earned her Ph.D. in microbiology and immunology through the dual graduate partnership program with Georgetown University and NIH.

Select Publications

1. Wu J, Xia L, Yao X, et al. The E3 ubiquitin ligase MARCH1 regulates antimalaria immunity through interferon signaling and T cell activation. Proc Natl Acad Sci U S A. 2020;117(28):16567-16578. Available from: https://www.pnas.org/content/117/28/16567.long
2. He X, Ashbrook AW, Du Y, et al. RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology. Proc Natl Acad Sci U S A. 2020;117(32):19465-19474. Available from: https://www.pnas.org/content/117/32/19465.long
3. He X, Xia L, Tumas KC, Wu J, Su XZ. Type I interferons and malaria: a double-edge sword against a complex parasitic disease. Front Cell Infect Microbiol. 2020;10:594621. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738626/
4. Peng YC, Qi Y, Zhang C, et al. Plasmodium yoelii erythrocyte-binding-like protein modulates host cell membrane structure, immunity, and disease severity. mBio. 2020;11(1):e02995-19. Available from: https://journals.asm.org/doi/10.1128/mBio.02995-19
5. Xia L, Wu J, Pattaradilokrat S, et al. Detection of host pathways universally inhibited after Plasmodium yoelii infection for immune intervention. Sci Rep. 2018;8(1):15280. Available from: https://www.nature.com/articles/s41598-018-33599-1